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近红外光谱技术在晚期杜普伊特伦挛缩症严重挛缩关节的安全性增强及个体化牵张中的应用

Application of Near Infrared Spectroscopy to Enhance Safety and Individualize Distraction of Severely Contracted Joints in Far-Advanced Dupuytren's Disease.

作者信息

Müller-Seubert Wibke, Cai Aijia, Horch Raymund E

机构信息

Department of Plastic and Hand Surgery and Laboratory for Tissue Engineering and Regenerative Medicine, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nürnberg (FAU), 91054 Erlangen, Germany.

出版信息

J Clin Med. 2024 Jul 10;13(14):4025. doi: 10.3390/jcm13144025.

Abstract

: Slow distraction of contracted joints is a well-established treatment in far-advanced stages of Dupuytren's disease (DD). To assess finger perfusion and avoid malperfusion, we studied near infrared spectroscopy (NIRS) to evaluate the maximum extent of distraction that would not harm microcirculation to the finger. This technique also allows an optimized treatment in accordance with sufficient blood perfusion during distraction. : Eligible patients with stage IV finger contractures who needed treatment for Dupuytren's contracture were included and prospectively investigated. The operation was performed with local anaesthesia. First, the Dupuytren strand of the treated finger was dissected in the palm to allow distraction. Under X-ray control, the distraction device was applied. Then, slow distraction of the treated joint was performed to evaluate the finger perfusion. To assess perfusion of the treated finger, NIRS was used to measure tissue oxygen saturation. If impaired finger perfusion was detected, traction was reduced until sufficient oxygen levels and perfusion patterns were reestablished. : NIRS was performed after application of the distraction device in seven cases. We treated six male and one female patient (mean age 70 years, range 51-80 years). Rapid distraction resulted in malperfusion of the treated fingers. Using NIRS proved to render reliable and reproducible information on finger perfusion and oxygenation in all seven patients. : Application of NIRS enhances safety in the treatment of far-advanced DD finger contractures with an external skeletal distraction device. It is non-invasive, reproducible, easy to use and allows for an individualized adapted distraction velocity.

摘要

对于晚期掌腱膜挛缩症(DD),缓慢牵引挛缩关节是一种行之有效的治疗方法。为了评估手指灌注情况并避免灌注不良,我们研究了近红外光谱技术(NIRS),以确定不会损害手指微循环的最大牵引程度。该技术还能在牵引过程中根据充足的血液灌注实现优化治疗。纳入需要治疗掌腱膜挛缩症的IV期手指挛缩合格患者,并进行前瞻性研究。手术采用局部麻醉。首先,在手掌中解剖治疗手指的掌腱膜束以进行牵引。在X射线控制下,应用牵引装置。然后,对治疗关节进行缓慢牵引以评估手指灌注。为评估治疗手指的灌注情况,使用NIRS测量组织氧饱和度。如果检测到手指灌注受损,则减少牵引,直到恢复足够的氧水平和灌注模式。在7例患者中,应用牵引装置后进行了NIRS检查。我们治疗了6名男性和1名女性患者(平均年龄70岁,范围51 - 80岁)。快速牵引导致治疗手指灌注不良。在所有7例患者中,使用NIRS均能提供关于手指灌注和氧合的可靠且可重复的信息。应用NIRS可提高使用外部骨骼牵引装置治疗晚期DD手指挛缩症的安全性。它具有非侵入性、可重复性、易于使用的特点,并允许进行个体化的适应性牵引速度调整。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d60f/11277288/d26bb56ff304/jcm-13-04025-g001.jpg

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