Department of Plastic Surgery, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Department of Surgery, Baylor College of Medicine, Houston, Texas, USA.
Int Wound J. 2024 Mar;21(3):e14814. doi: 10.1111/iwj.14814.
Our objective was to evaluate normative data for near-infrared spectroscopy (NIRS) in 110 healthy volunteers by Fitzpatrick skin type (FST) and region of the foot. We obtained measurements of the dorsum and plantar foot using a commercially available device (SnapshotNIR, Kent Imaging, Calgary Canada). On the dorsum of the foot, people with FST6 had significantly lower oxygen saturation compared to FST1-5 (p < 0.001), lower oxyhaemoglobin compared to FST2-5 (p = 0.001), but there was no difference in deoxyhaemoglobin. No differences were found on the plantar foot. When comparing dorsal and plantar foot, there was higher oxyhaemoglobin (0.40 ± 0.09 vs. 0.51 ± 0.12, p < 0.001) and deoxyhaemoglobin (0.16 ± 0.05 vs. 0.21 ± 0.05, p < 0.001) on the plantar foot, but no differences in oxygen saturation (dorsal 70.7 ± 10.8, plantar 70.0 ± 9.5, p = 0.414). In 6.4% of feet, there were black areas, for which no NIRS measurements could be generated. All areas with no data were on the dorsal foot and only found in FST 5-6. People with FST6 had significantly larger areas with no data compared to FST 5 (22.2 cm ± 20.4 vs. 1.9 cm ± 0.90, p = 0.007). These findings should be considered when using NIRS technology. Skin pigmentation should be evaluated in future NIRS studies.
我们的目标是通过皮肤类型（FST）和足部区域评估 110 名健康志愿者近红外光谱（NIRS）的参考值。我们使用市售设备（加拿大卡尔加里 Kent Imaging 的 SnapshotNIR）测量足部背侧和足底的 NIRS 数据。在足部背侧，FST6 的人群与 FST1-5 相比，氧饱和度显著降低（p<0.001），与 FST2-5 相比，氧合血红蛋白显著降低（p=0.001），但脱氧血红蛋白无差异。足底无差异。比较背侧和足底，足底的氧合血红蛋白（0.40±0.09 比 0.51±0.12，p<0.001）和脱氧血红蛋白（0.16±0.05 比 0.21±0.05，p<0.001）更高，但氧饱和度无差异（背侧 70.7±10.8，足底 70.0±9.5，p=0.414）。在 6.4%的足部存在黑色区域，无法进行 NIRS 测量。所有无数据的区域均位于足部背侧，仅在 FST 5-6 中发现。FST6 的人群与 FST5 相比，无数据区域显著更大（22.2±20.4cm2 比 1.9±0.90cm2，p=0.007）。在使用 NIRS 技术时应考虑这些发现。未来的 NIRS 研究应评估皮肤色素沉着。
