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子宫间质肿瘤:病理学、分子图谱和治疗学的最新进展。

Uterine Mesenchymal Tumors: Updates on Pathology, Molecular Landscape, and Therapeutics.

机构信息

Pathology Department, King Fahd University Hospital, College of Medicine, Imam Abdulrahman Bin Faisal University, P.O. Box 1982, Dammam 31441, Saudi Arabia.

出版信息

Medicina (Kaunas). 2024 Jul 2;60(7):1085. doi: 10.3390/medicina60071085.

Abstract

Mesenchymal uterine tumors are a diverse group of neoplasms with varying biological potential. Many of these neoplasms can have overlapping morphologic similarities, which, in some instances, render their diagnosis and categorization thorough histomorphologic examination inconclusive. In the last decade, an exponential amount of molecular data aiming to more accurately characterize and, consequently, treat these tumors have accumulated. The goal of this narrative review is to provide a pathologic review, a genetic update, and to know the new therapeutic avenues of primary uterine mesenchymal neoplasms.

摘要

间质子宫肿瘤是一组具有不同生物学潜能的多种肿瘤。其中许多肿瘤具有重叠的形态学相似性,在某些情况下,仅凭组织形态学检查无法明确诊断和分类。在过去十年中,积累了大量旨在更准确地描述这些肿瘤并因此进行治疗的分子数据。本文的目的是提供原发性子宫间质肿瘤的病理复习、遗传更新和新的治疗途径。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/19b9/11278911/38be94a52eed/medicina-60-01085-g001.jpg

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