Department of Anesthesiology and Pain Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, Republic of Korea.
Department of Anesthesiology and Pain Medicine, Yeouido St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, Republic of Korea.
Medicina (Kaunas). 2024 Jul 15;60(7):1135. doi: 10.3390/medicina60071135.
: Postoperative nausea and vomiting (PONV) is a common issue for females undergoing gynecological surgeries, including those assisted by robotic systems. Despite available prophylactic measures, the incidence of PONV remains high, negatively impacting recovery and increasing healthcare costs. This study evaluates whether preoperative gum chewing reduces the need for anti-emetic drugs in females undergoing robot-assisted laparoscopic surgery for benign ovarian mass. : This prospective, single-blinded, randomized controlled trial enrolled 92 adult females scheduled for robot-assisted laparoscopic surgery to treat benign ovarian mass. Following exclusions, the remaining participants were randomly assigned to either a gum-chewing group or a no-gum-chewing group. The gum-chewing group chewed sugar-free gum for 15 min in the holding area before surgery. The primary outcome measured was the need for anti-emetics to control PONV during the first hour in the post-anesthesia care unit (PACU). Secondary outcomes included the number of anti-emetic requests. No preemptive anti-emetics were administered during surgery. : Out of the initial 92 patients, 88 were included in the final analysis, with 44 in each group. The incidence of PONV requiring anti-emetics in the PACU was significantly lower in the gum-chewing group (79.5%) compared to the no-gum-chewing group (95.5%). Additionally, the number of anti-emetic requests was higher in the no-gum-chewing group. No postoperative complications such as tooth or jaw pain/injury or gastric content regurgitation were reported. : Preoperative gum chewing for 15 min immediately before surgery significantly reduced the incidence of PONV in females undergoing robot-assisted laparoscopic surgery for benign ovarian mass. This simple, non-pharmacological intervention improved patient comfort and reduced the need for anti-emetic medications without any adverse effects. Further studies are needed to confirm these findings and to develop guidelines for incorporating preoperative gum chewing into clinical practice.
术后恶心和呕吐（PONV）是接受妇科手术的女性常见问题，包括使用机器人系统辅助的手术。尽管有预防措施，PONV 的发生率仍然很高，对恢复产生负面影响，并增加医疗保健成本。本研究评估了术前咀嚼口香糖是否可以减少因良性卵巢肿块而行机器人辅助腹腔镜手术的女性对止吐药物的需求。
这是一项前瞻性、单盲、随机对照试验，共纳入 92 名计划接受机器人辅助腹腔镜手术治疗良性卵巢肿块的成年女性。排除后，其余参与者被随机分配到咀嚼口香糖组或不咀嚼口香糖组。咀嚼口香糖组在手术前的等候区咀嚼无糖口香糖 15 分钟。主要观察指标是在麻醉后护理单元（PACU）的前 1 小时内需要止吐药物来控制 PONV 的情况。次要观察指标包括需要止吐药物的次数。手术期间没有给予预防性止吐药物。
在最初的 92 名患者中，88 名患者被纳入最终分析，每组 44 名。在 PACU 中需要止吐药物的 PONV 发生率在咀嚼口香糖组（79.5%）明显低于不咀嚼口香糖组（95.5%）。此外，不咀嚼口香糖组要求使用止吐药物的次数更多。没有报告术后并发症，如牙齿或颌骨疼痛/损伤或胃内容物反流。
术前咀嚼口香糖 15 分钟可显著降低因良性卵巢肿块而行机器人辅助腹腔镜手术的女性 PONV 的发生率。这种简单的非药物干预措施改善了患者的舒适度，减少了对止吐药物的需求，没有任何不良反应。需要进一步的研究来证实这些发现，并制定将术前咀嚼口香糖纳入临床实践的指南。
