Guerra M D, Peters V M
Rev Bras Pesqui Med Biol. 1979 Jun;12(2-3):185-8.
The aim of this work was to observe the starting of fetal macrosomy during the gestation of the diabetic rat and whether the sex of the fetuses has any influence on it. Lesions were produced in the B cells of the pancreas by the administration of alloxan on the 4th gestation day. The length and weight of the fetuses were not altered by this treatment before the 14th day of pregnancy, suggesting that fetal macrosomy should occur after this day.
这项工作的目的是观察糖尿病大鼠妊娠期巨大胎儿的起始情况,以及胎儿性别是否对其有任何影响。在妊娠第4天通过给予四氧嘧啶对胰腺的B细胞造成损伤。在怀孕第14天之前,这种处理并未改变胎儿的长度和体重,这表明巨大胎儿应在这一天之后出现。