Center for Neural Science, New York University, New York, NY 10003, USA.
Center for Neural Science, New York University, New York, NY 10003, USA.
Cell Rep. 2024 Aug 27;43(8):114534. doi: 10.1016/j.celrep.2024.114534. Epub 2024 Jul 26.
To determine whether post-natal improvements in form vision result from changes in mid-level visual cortex, we studied neuronal and behavioral responses to texture stimuli that were matched in local spectral content but varied in "naturalistic" structure. We made longitudinal measurements of visual behavior from 16 to 95 weeks of age, and of neural responses from 20 to 56 weeks. We also measured behavioral and neural responses in near-adult animals more than 3 years old. Behavioral sensitivity reached half-maximum around 25 weeks of age, but neural sensitivities remained stable through all ages tested. Neural sensitivity to naturalistic structure was highest in V4, lower in V2 and inferotemporal cortex (IT), and barely discernible in V1. Our results show a dissociation between stable neural performance and improving behavioral performance, which may reflect improved processing capacity in circuits downstream of visual cortex.
为了确定形态视觉的产后改善是否源于中水平视觉皮层的变化，我们研究了对纹理刺激的神经元和行为反应，这些刺激在局部光谱内容上匹配，但在“自然”结构上有所不同。我们从 16 周到 95 周龄进行了视觉行为的纵向测量，从 20 周到 56 周龄进行了神经反应的测量。我们还在 3 岁以上的成年动物中测量了行为和神经反应。行为敏感性在 25 周龄左右达到最大值，但所有测试年龄的神经敏感性都保持稳定。对自然结构的神经敏感性在 V4 最高，在 V2 和下颞叶皮层（IT）较低，在 V1 几乎难以察觉。我们的结果表明，神经性能的稳定与行为性能的改善之间存在分离，这可能反映了视觉皮层下游回路处理能力的提高。
