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神经科学中更好推断的估计。

Estimation for Better Inference in Neuroscience.

机构信息

Dominican University, River Forest, Illinois 60305.

La Trobe University, Melbourne, Victoria 3086, Australia.

出版信息

eNeuro. 2019 Aug 1;6(4). doi: 10.1523/ENEURO.0205-19.2019. eCollection 2019 Jul-Aug.

DOI:10.1523/ENEURO.0205-19.2019
PMID:31453316
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6709209/
Abstract

The estimation approach to inference emphasizes reporting effect sizes with expressions of uncertainty (interval estimates). In this perspective we explain the estimation approach and describe how it can help nudge neuroscientists toward a more productive research cycle by fostering better planning, more thoughtful interpretation, and more balanced evaluation of evidence.

摘要

估计推理方法强调用不确定度的表达(区间估计)来报告效应量。从这个角度出发,我们解释了估计推理方法,并描述了它如何通过促进更好的规划、更深入的解释以及更平衡的证据评估来帮助神经科学家进入更富有成效的研究周期。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27a3/6709209/00afc242dbc6/enu9991929800002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27a3/6709209/d06287b93346/enu9991929800001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27a3/6709209/00afc242dbc6/enu9991929800002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27a3/6709209/d06287b93346/enu9991929800001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27a3/6709209/00afc242dbc6/enu9991929800002.jpg

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2
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3
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4
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