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自发性脉络膜上腔出血:临床特征、视力预后和预测因素。

Spontaneous suprachoroidal haemorrhage: clinical features, visual outcomes and prognosis factors.

机构信息

Moorfields Eye Hospital NHS Foundation Trust, London, UK.

Department of Ophthalmology, Inselspital, University Hospital of Bern, Bern, Switzerland.

出版信息

Eye (Lond). 2024 Dec;38(17):3285-3289. doi: 10.1038/s41433-024-03278-9. Epub 2024 Jul 28.

Abstract

BACKGROUND

To describe clinical features, risk factors and outcomes of patients with diagnosis of rare spontaneous suprachoroidal haemorrhage (SSCH) over a 20-year period from a tertiary eye unit.

METHODS

Retrospective, observational case-series of patients with SSCH, defined as SCH without a known cause at diagnosis. Variables analysed included age, gender, ethnicity, systemic and ocular comorbidities, systemic medication, initial and final best corrected visual acuity (BCVA), clinical features, management and follow-up.

RESULTS

Total of 11 eyes of 11 patients were identified. Median age was 70 years (SD 25.9). Most patients were female (82%) and white British. Median follow-up period was 2.2 years. Hypertension was the most frequently associated underlying systemic disease (45%) and 36% were on anti-coagulant or anti-platelet therapy. High myopia was observed in 36% of cases. Presenting BCVA of 1.00 logMAR or better was a positive predictor of final BCVA. No significant improvement in the initial versus final BCVA was found in patients who underwent surgery versus those who remained under observation.

CONCLUSION

Patients over 60 years-old with hypertension, anticoagulant treatment, high myopia, and pseudophakia were common. Visual outcomes were poor, surgical intervention had limited impact. Good initial BCVA predicted better final acuity while extensive SSCH correlated with poorer visual results. Despite the study's limitations, this series offers valuable insights into visual prognosis and prognostic factors.

摘要

背景

描述一个三级眼科中心在 20 年期间诊断出的罕见自发性脉络膜上腔出血(SSCH)患者的临床特征、危险因素和结局。

方法

回顾性观察性病例系列研究,纳入诊断为 SCH 但无明确病因的 SSCH 患者。分析的变量包括年龄、性别、种族、全身和眼部合并症、全身用药、初始和最终最佳矫正视力(BCVA)、临床特征、治疗和随访。

结果

共发现 11 例 11 眼。中位年龄为 70 岁(SD 25.9)。大多数患者为女性(82%)和白种英国人。中位随访时间为 2.2 年。高血压是最常见的潜在系统性疾病(45%),36%的患者正在接受抗凝或抗血小板治疗。36%的病例存在高度近视。初始 BCVA 为 1.00 logMAR 或更好是最终 BCVA 的阳性预测因子。与接受手术的患者相比,接受观察治疗的患者在初始和最终 BCVA 之间没有发现显著改善。

结论

60 岁以上患有高血压、抗凝治疗、高度近视和白内障的患者较为常见。视力预后较差,手术干预影响有限。良好的初始 BCVA 预测最终视力较好,而广泛的 SSCH 与较差的视力结果相关。尽管本研究存在局限性,但该系列提供了有价值的关于视力预后和预后因素的见解。

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本文引用的文献

1
Suprachoroidal Hemorrhage.脉络膜上腔出血
Ophthalmologica. 2023;246(5-6):255-277. doi: 10.1159/000533937. Epub 2023 Sep 2.
2
Spontaneous Expulsive Suprachoroidal Hemorrhage.自发性脉络膜上腔出血性驱逐
Am J Emerg Med. 2023 Aug;70:210.e1-210.e3. doi: 10.1016/j.ajem.2023.06.008. Epub 2023 Jun 8.
6
Spontaneous suprachoroidal hemorrhage: Case report and review of the literature.自发性脉络膜上腔出血:病例报告及文献综述
Taiwan J Ophthalmol. 2016 Jan-Mar;6(1):36-41. doi: 10.1016/j.tjo.2014.10.008. Epub 2015 Jan 20.

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