Li S J, Ma X H, Yin Z Y, Feng Q Y, Tian Z Z, Wang H M, Fang Q H
Department of Pulmonary and Critical Care Medicine, Beijing Huairou Hospital, Beijing 101400, China.
Department of Infectious Disease, Beijing Huairou Hospital, Beijing 101400, China.
Zhonghua Jie He He Hu Xi Za Zhi. 2024 Aug 12;47(8):761-766. doi: 10.3760/cma.j.cn112147-20240113-00028.
A 58-year-old man was admitted with a typical presentation of acute left heart failure. However, the patient showed a partial response to the anti-heart failure therapy. Following admission, a continuous fever was monitored, and a CT scan revealed that multiple opacities on bilateral lungs had progressed. Bronchoscopy was performed, and was detected by Metagenomic next-generation sequencing (mNGS) in bronchoalveolar lavage (BALF), and transbronchial lung biopsy showed organizing pneumonia. Considering that the patient had a history of rabbit breeding and delivery, with some newborn rabbits dying before he became ill, organizing pneumonia secondary to Q fever pneumonia was diagnosed. Anti-Q fever treatment was initiated and the patient's temperature returned to normal. Glucocorticoid was administered after adequate treatment for Q fever. The patient's symptom of dyspnea relieved soon and opacities on CT scan were absorbed remarkably. The final diagnosis was organizing pneumonia secondary to Q fever pneumonia accompanied with left heart failure.
一名58岁男性因急性左心衰竭的典型表现入院。然而,患者对抗心力衰竭治疗反应欠佳。入院后,持续监测到发热,CT扫描显示双肺多发混浊影进展。进行了支气管镜检查,通过宏基因组下一代测序(mNGS)在支气管肺泡灌洗(BALF)中检测到病原体,经支气管肺活检显示为机化性肺炎。考虑到患者有兔子饲养和接生史,在他生病前有一些新生兔子死亡,诊断为Q热肺炎继发的机化性肺炎。开始进行抗Q热治疗,患者体温恢复正常。在对Q热进行充分治疗后给予糖皮质激素。患者的呼吸困难症状很快缓解,CT扫描上的混浊影明显吸收。最终诊断为Q热肺炎继发的机化性肺炎伴左心衰竭。