一份采用下一代宏基因组测序技术低读长检测贝氏柯克斯体基因组的急性 Q 热病例报告。

A case report of acute Q fever with low-read detection of Coxiella burnetii genome by next-generation metagenomic sequencing.

机构信息

Department of Laboratory Medicine, Shenzhen Guangming District People's Hospital, Shenzhen, Guangdong, China.

Center for Medical Experiments (CME), Shenzhen Guangming District People's Hospital, Shenzhen, 518106, Guangdong, China.

出版信息

Diagn Microbiol Infect Dis. 2024 Oct;110(2):116434. doi: 10.1016/j.diagmicrobio.2024.116434. Epub 2024 Jul 14.

DOI:10.1016/j.diagmicrobio.2024.116434

PMID:39111107

Abstract

The case presents a 47-year-old man with sudden abdominal pain and fever, but the cause was uncertain. Through metagenomic next-generation sequencing (mNGS) and detecting Q fever antibodies in serum, along with the patient's clinical and epidemiological history, a precise diagnosis was made, enabling timely and proper treatment.

摘要

本病例为一位 47 岁男性，突发腹痛和发热，但病因不明。通过宏基因组下一代测序（mNGS）和血清中 Q 热抗体检测，并结合患者的临床和流行病学史，明确了诊断，从而能够及时进行恰当的治疗。