Sukharev A M, Kulemin V V, Borodiiuk N A, Dunaev G A, Isakova M I
Ter Arkh. 1985;57(8):118-21.
Gel precipitation was employed to detect antibodies to the A-polysaccharide specific antigenic determinant in blood serum of 131 patients with different versions of rheumatic fever. 21 patients with non-rheumatic myocarditis, 25 convalescents following quinsy, and 58 donors. It was established that high titers of antibodies to A-polysaccharide in patients with protracted and latent rheumatic fever correlate with the clinical and morphological signs of the process activity. Elevation of the antibody titers after mitral commissurotomy made to 107 patients was recorded only in those with exacerbation or activation of rheumatic fever. During the first year after mitral commissurotomy as well as at the preoperative period, the titers of antibodies to A-polysaccharide in patients with protracted rheumatic fever were higher than in those with latent and inactive disease patterns.
采用凝胶沉淀法检测了131例不同类型风湿热患者血清中针对A多糖特异性抗原决定簇的抗体。21例非风湿性心肌炎患者、25例扁桃体炎康复者以及58名献血者。结果发现，迁延性和潜伏性风湿热患者中A多糖抗体的高滴度与疾病活动的临床和形态学征象相关。对107例患者进行二尖瓣分离术后，仅在风湿热加重或活动的患者中记录到抗体滴度升高。在二尖瓣分离术后的第一年以及术前阶段，迁延性风湿热患者的A多糖抗体滴度高于潜伏性和非活动性疾病患者。
