Munagama Chathuri Lakna, Silva Shehan
University Medical Unit, Colombo South Teaching Hospital, Kalubowila, Sri Lanka.
Faculty of Medical Sciences, University of Sri Jayewardenepura, Nugegoda, Sri Lanka.
SAGE Open Med Case Rep. 2024 Jul 26;12:2050313X241266558. doi: 10.1177/2050313X241266558. eCollection 2024.
Niacin (Vitamin B3) plays a crucial role as a vitamin in cellular energy production, metabolism, and DNA repair. A severe deficiency of this vitamin can lead to pellagra, which is characterized by dermatitis, dementia, diarrhoea and eventually death if untreated. A 68-year-old woman with a poor socioeconomic background presented with photosensitive dermatitis, fever, abdominal pain, and diarrhoea. Her urine changed to port wine colour following sun exposure. Porphyria cutanea tarda was excluded in the absence of demonstrable urine spectrophotometry. A diagnosis of pellagra was made, and timely management led to a complete cure. Proper diagnosis and effective treatment of pellagra are imperative as this condition can be life-threatening if left untreated.
烟酸(维生素B3)作为一种维生素,在细胞能量产生、新陈代谢和DNA修复过程中发挥着关键作用。严重缺乏这种维生素会导致糙皮病,其特征为皮炎、痴呆、腹泻,若不治疗最终会导致死亡。一名社会经济背景较差的68岁女性出现了光敏性皮炎、发热、腹痛和腹泻症状。日晒后她的尿液变成了葡萄酒色。由于尿液分光光度法未显示异常,排除了迟发性皮肤卟啉症。诊断为糙皮病,及时治疗使其完全康复。糙皮病的正确诊断和有效治疗至关重要,因为这种疾病若不治疗可能会危及生命。