Suppr超能文献

伴有黑尿的糙皮病非典型表现:一个临床难题。

Atypical presentation of pellagra with black urine: A clinical conundrum.

作者信息

Munagama Chathuri Lakna, Silva Shehan

机构信息

University Medical Unit, Colombo South Teaching Hospital, Kalubowila, Sri Lanka.

Faculty of Medical Sciences, University of Sri Jayewardenepura, Nugegoda, Sri Lanka.

出版信息

SAGE Open Med Case Rep. 2024 Jul 26;12:2050313X241266558. doi: 10.1177/2050313X241266558. eCollection 2024.

Abstract

Niacin (Vitamin B3) plays a crucial role as a vitamin in cellular energy production, metabolism, and DNA repair. A severe deficiency of this vitamin can lead to pellagra, which is characterized by dermatitis, dementia, diarrhoea and eventually death if untreated. A 68-year-old woman with a poor socioeconomic background presented with photosensitive dermatitis, fever, abdominal pain, and diarrhoea. Her urine changed to port wine colour following sun exposure. Porphyria cutanea tarda was excluded in the absence of demonstrable urine spectrophotometry. A diagnosis of pellagra was made, and timely management led to a complete cure. Proper diagnosis and effective treatment of pellagra are imperative as this condition can be life-threatening if left untreated.

摘要

烟酸(维生素B3)作为一种维生素,在细胞能量产生、新陈代谢和DNA修复过程中发挥着关键作用。严重缺乏这种维生素会导致糙皮病,其特征为皮炎、痴呆、腹泻,若不治疗最终会导致死亡。一名社会经济背景较差的68岁女性出现了光敏性皮炎、发热、腹痛和腹泻症状。日晒后她的尿液变成了葡萄酒色。由于尿液分光光度法未显示异常,排除了迟发性皮肤卟啉症。诊断为糙皮病,及时治疗使其完全康复。糙皮病的正确诊断和有效治疗至关重要,因为这种疾病若不治疗可能会危及生命。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a8b2/11282565/7903538c6fe4/10.1177_2050313X241266558-fig1.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验