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大型手术病例系列中鹰综合征的表现及结果

Eagle syndrome presentation and outcomes in a large surgical case series.

作者信息

Held Michael E, Farsi Soroush, Creighton Erin R Weatherford, Davis Kyle P, King Deanne L, Suen James Y

机构信息

Department of Otolaryngology University of Arkansas Medical Sciences Little Rock Arkansas USA.

出版信息

Laryngoscope Investig Otolaryngol. 2024 Jul 26;9(4):e1289. doi: 10.1002/lio2.1289. eCollection 2024 Aug.

DOI:10.1002/lio2.1289
PMID:39071203
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11273210/
Abstract

OBJECTIVE

The purpose of this study is to describe both the common and uncommon symptoms associated with Eagle syndrome and share our experience treating a large group of patients with surgical intervention, primarily intraoral excision of the calcified stylohyoid ligament.

METHODS

This retrospective case series included 56 patients at least 18 years of age or older with a diagnosis of Eagle syndrome. All operations were conducted by a single surgeon at a tertiary medical center from 2015 to 2022. Charts were reviewed for demographics, prior medical/surgical history, symptoms, imaging results, operative details, and follow-up history. A phone survey inquired about presenting symptoms and symptom resolution following surgery.

RESULTS

The most common areas of pain were the ear (64.3%), underneath the angle of the mandible (50%), throat (46.4%), and neck (30.4%). Over 70% of patients reported tinnitus, dysphagia, and pain that were exacerbated by head rotation. Fifty-one of the 56 patients underwent surgical treatment, 92.2% via intraoral and 7.8% via cervical approaches. All patients (100%) reached in a phone survey stated that their symptoms resolved or improved after surgery.

CONCLUSION

Eagle syndrome typically presents with common symptoms. However, healthcare providers must also be vigilant for less common manifestations, such as seizures or episodes of dizziness/fainting. These may be caused by calcification of the stylohyoid ligament. Intraoral surgical resection of the calcified ligament is a safe and effective treatment for most patients.

LEVEL OF EVIDENCE

Level 4.

摘要

目的

本研究旨在描述与鹰综合征相关的常见和不常见症状,并分享我们对一大群患者进行手术干预(主要是经口切除钙化的茎突舌骨韧带)的治疗经验。

方法

本回顾性病例系列研究纳入了56例年龄在18岁及以上、诊断为鹰综合征的患者。所有手术均由一名外科医生于2015年至2022年在一家三级医疗中心进行。查阅病历以获取人口统计学资料、既往医疗/手术史、症状、影像学检查结果、手术细节和随访史。通过电话调查询问患者的症状表现以及术后症状缓解情况。

结果

最常见的疼痛部位是耳部(64.3%)、下颌角下方(50%)、咽喉部(46.4%)和颈部(30.4%)。超过70%的患者报告耳鸣、吞咽困难以及头部转动时疼痛加剧。56例患者中有51例接受了手术治疗,其中92.2%通过经口途径,7.8%通过颈部途径。在电话调查中表示的所有患者(100%)称术后症状缓解或改善。

结论

鹰综合征通常表现为常见症状。然而,医疗服务提供者也必须警惕不常见的表现,如癫痫发作或头晕/昏厥发作。这些可能由茎突舌骨韧带钙化引起。对于大多数患者,经口手术切除钙化韧带是一种安全有效的治疗方法。

证据级别

4级。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9841/11273210/8deae3cde378/LIO2-9-e1289-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9841/11273210/ad85afa2566f/LIO2-9-e1289-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9841/11273210/d81a0d542395/LIO2-9-e1289-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9841/11273210/8deae3cde378/LIO2-9-e1289-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9841/11273210/ad85afa2566f/LIO2-9-e1289-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9841/11273210/d81a0d542395/LIO2-9-e1289-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9841/11273210/8deae3cde378/LIO2-9-e1289-g002.jpg

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本文引用的文献

1
Bilateral elongated styloid processes: Eagle syndrome.双侧茎突过长:鹰综合征。
Lancet. 2021 Apr 10;397(10282):1387. doi: 10.1016/S0140-6736(21)00531-6.
2
Surgical management of Eagle syndrome: A 17-year experience with open and transoral robotic styloidectomy.Eagle 综合征的手术治疗:经口机器人和开放性茎突截骨术 17 年经验。
Am J Otolaryngol. 2020 Mar-Apr;41(2):102324. doi: 10.1016/j.amjoto.2019.102324. Epub 2019 Nov 12.
3
Management of stylohyoid syndrome: A systematic review following PRISMA guidelines.茎突综合征的治疗:一项遵循 PRISMA 指南的系统综述。
Eur Ann Otorhinolaryngol Head Neck Dis. 2019 Sep;136(4):281-287. doi: 10.1016/j.anorl.2019.05.002. Epub 2019 May 21.
4
Eagle Syndrome as a Cause of Cerebral Venous Sinus Thrombosis.Eagle 综合征致脑静脉窦血栓形成 1 例
Can J Neurol Sci. 2019 May;46(3):344-345. doi: 10.1017/cjn.2019.17. Epub 2019 Apr 1.
5
Eagle's syndrome: a case report and CT pictorial review.伊格尔综合征:一例病例报告及CT图像综述
Radiol Case Rep. 2018 Oct 30;14(2):141-145. doi: 10.1016/j.radcr.2018.10.008. eCollection 2019 Feb.
6
Bilateral Ischemic Stroke Due to Carotid Artery Compression by Abnormally Elongated Styloid Process at Both Sides: A Case Report.双侧异常伸长茎突压迫颈动脉致双侧缺血性脑卒中:一例报告
J Stroke Cerebrovasc Dis. 2018 Jun;27(6):e89-e91. doi: 10.1016/j.jstrokecerebrovasdis.2017.12.018. Epub 2018 Jan 19.
7
Treatment of Eagle syndrome with transcervical approach secondary to a failed intraoral attempt: Surgical technique and literature review.经口尝试失败后经颈入路治疗鹰嘴综合征:手术技术及文献综述
J Stomatol Oral Maxillofac Surg. 2017 Dec;118(6):353-358. doi: 10.1016/j.jormas.2017.06.017. Epub 2017 Jul 10.
8
Eagle syndrome: A comprehensive review.鹰嘴综合征:一项全面综述。
Clin Neurol Neurosurg. 2017 Aug;159:34-38. doi: 10.1016/j.clineuro.2017.04.021. Epub 2017 May 6.
9
A rare fatality due to calcified stylohyoid ligament (Eagle syndrome).
Med Leg J. 2017 Jun;85(2):103-104. doi: 10.1177/0025817217695139. Epub 2017 Jan 1.
10
Carotid artery dissection: a rare complication of Eagle syndrome.颈动脉夹层:伊格尔综合征的一种罕见并发症。
BMJ Case Rep. 2017 Mar 13;2017:bcr2016218184. doi: 10.1136/bcr-2016-218184.