Boonplod Chanakrit, Wannasopha Yutthaphan, Tantraworasin Apichat, Kongkarnka Sarawut, Wannasai Komson
Medical Student, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
Department of Radiology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
Heliyon. 2024 Jun 28;10(13):e33913. doi: 10.1016/j.heliyon.2024.e33913. eCollection 2024 Jul 15.
Mature intrapulmonary cystic teratomas are rare. The clinical manifestations are nonspecific and may mislead to other diseases. The radiographic findings are often perplexing. There are few complete reports on intrapulmonary teratomas, including patient history, radiologic and pathologic findings, patient management, and outcomes. We present a case report of an intrapulmonary mature cystic teratoma diagnosed at our hospital, along with an extensive review of the relevant literature.
A 47-year-old non-smoking female patient presented with hemoptysis and intermittent dyspnea for 5 months without fever or weight loss. Chest computed tomography revealed an inhomogeneous, hypodense, lobulated mass with internal fat, calcification, and soft tissue components. The patient underwent a left thoracotomy and left upper lobe lobectomy. Pathological examination revealed a cystic tumor containing various components, including fat, keratin debris, teeth, and hair. A diagnosis of intrapulmonary mature cystic teratoma was made. Three months after the operation, no recurrent tumor was identified, and the patient was scheduled for follow-up next year.
Intrapulmonary mature cystic teratomas are unusual. Owing to its general clinical symptoms and radiographic findings, it was misdiagnosed before surgery. After surgery, pathological and radiological findings confirmed the diagnosis. Therefore, intrapulmonary mature cystic teratomas should be considered in the differential diagnosis, and sufficient examinations should be conducted to rule out the condition.
成熟型肺内囊性畸胎瘤较为罕见。其临床表现缺乏特异性,可能会误诊为其他疾病。影像学表现常令人困惑。关于肺内畸胎瘤,包括患者病史、放射学和病理学表现、患者管理及预后等方面的完整报告较少。我们报告一例在我院诊断的肺内成熟型囊性畸胎瘤病例,并对相关文献进行广泛回顾。
一名47岁不吸烟女性患者,出现咯血和间歇性呼吸困难5个月,无发热或体重减轻。胸部计算机断层扫描显示一个不均匀、低密度、分叶状肿块,内部有脂肪、钙化和软组织成分。患者接受了左开胸手术及左上叶肺叶切除术。病理检查显示一个囊性肿瘤,包含多种成分,如脂肪、角蛋白碎屑、牙齿和毛发。诊断为肺内成熟型囊性畸胎瘤。术后3个月,未发现肿瘤复发,患者计划于次年进行随访。
肺内成熟型囊性畸胎瘤较为罕见。因其一般临床症状和影像学表现,术前被误诊。手术后,病理和影像学检查结果证实了诊断。因此,在鉴别诊断中应考虑肺内成熟型囊性畸胎瘤,并应进行充分检查以排除该病。