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婴儿巨大肺内畸胎瘤的研究进展:一例报告及文献综述

Insights Into Giant Intrapulmonary Teratomas in Infants: A Case Report and Literature Review.

作者信息

Marhoon Sara E, Ali Ali H, Abdelmoneim Osama M, Eldesoky Tarek

机构信息

College of Medicine, Mansoura University, Mansoura, EGY.

Pediatrics, Mansoura University Children Hospital, Mansoura, EGY.

出版信息

Cureus. 2024 Jun 22;16(6):e62937. doi: 10.7759/cureus.62937. eCollection 2024 Jun.

DOI:10.7759/cureus.62937
PMID:39050352
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11265971/
Abstract

Mature cystic teratomas exhibit a variety of tissues within their pathology. In adults, teratomas typically originate in the gonads. However, one of the rarest origins is the lung, making intrapulmonary teratoma (IPT) exceedingly uncommon. In infants, extragonadal teratomas are more common, with only two cases of IPT reported in the literature. While the clinical presentation in infants and adults is similar, fever appears to be unique to infant cases. We present a case of a one-year-old female who exhibited respiratory distress and fever. A chest X-ray revealed an opaque right hemithorax, initially leading to a diagnosis of pneumonia. Despite intravenous (IV) antibiotic treatment, there was no improvement. A subsequent chest computed tomography (CT) scan revealed a large mass with heterogeneous densities occupying the entire right hemithorax, indicative of IPT. The mass was successfully excised, and the infant was discharged on the 11th postoperative day without complications. This case adds to the limited literature on giant IPT in infants compared to the two previously published cases.

摘要

成熟囊性畸胎瘤在其病理中表现出多种组织。在成年人中,畸胎瘤通常起源于性腺。然而,最罕见的起源之一是肺,这使得肺内畸胎瘤(IPT)极为罕见。在婴儿中,性腺外畸胎瘤更为常见,文献中仅报道了两例IPT。虽然婴儿和成年人的临床表现相似,但发热似乎是婴儿病例所特有的。我们报告一例1岁女性,表现为呼吸窘迫和发热。胸部X线显示右半胸不透明,最初诊断为肺炎。尽管进行了静脉抗生素治疗,但病情并无改善。随后的胸部计算机断层扫描(CT)显示一个密度不均匀的大肿块占据了整个右半胸,提示为IPT。肿块成功切除,婴儿术后第11天出院,无并发症。与之前发表的两例病例相比,该病例增加了关于婴儿巨大IPT的有限文献。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ccf/11265971/2dbca9dc0acd/cureus-0016-00000062937-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ccf/11265971/da74579df343/cureus-0016-00000062937-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ccf/11265971/2a1285cbbfdf/cureus-0016-00000062937-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ccf/11265971/2dbca9dc0acd/cureus-0016-00000062937-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ccf/11265971/da74579df343/cureus-0016-00000062937-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ccf/11265971/2a1285cbbfdf/cureus-0016-00000062937-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ccf/11265971/2dbca9dc0acd/cureus-0016-00000062937-i03.jpg

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本文引用的文献

1
Right upper lobe intrapulmonary mature cystic teratoma. An unusual location with unusual associations and a review of the literature.右上叶肺内成熟性囊性畸胎瘤。一个具有不寻常关联的不寻常部位及文献综述。
Int J Surg Case Rep. 2022 Jan;90:106683. doi: 10.1016/j.ijscr.2021.106683. Epub 2021 Dec 14.
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Intrapulmonary mature teratoma: an unusual finding.肺内成熟畸胎瘤:一项不寻常的发现。
Indian J Thorac Cardiovasc Surg. 2022 Jan;38(1):80-83. doi: 10.1007/s12055-021-01180-7. Epub 2021 Sep 3.
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Neonatal Malignant Disorders: Germ Cell Tumors.
新生儿恶性疾病:生殖细胞肿瘤。
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Isolated intrapulmonary teratoma.孤立性肺内畸胎瘤。
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AIRP best cases in radiologic-pathologic correlation: mediastinal mature cystic teratoma.放射学-病理学相关性最佳病例:纵隔成熟囊性畸胎瘤。
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Mature cystic teratoma of the lung.肺成熟囊性畸胎瘤。
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Giant intrapulmonary teratoma: a rare case.巨大肺内畸胎瘤:1例罕见病例
Case Rep Pulmonol. 2011;2011:298653. doi: 10.1155/2011/298653. Epub 2011 Sep 25.
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Intrapulmonary cystic teratoma mimicking malignant pulmonary neoplasm.酷似恶性肺肿瘤的肺内囊性畸胎瘤。
BMJ Case Rep. 2012 Aug 14;2012:bcr0220125770. doi: 10.1136/bcr.02.2012.5770.
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Teratomas in infants and children.婴幼儿畸胎瘤
Curr Opin Pediatr. 2009 Jun;21(3):344-9. doi: 10.1097/MOP.0b013e32832b41ee.