Chen Chong, Ye Wenlin, Yu Zhengran, Zheng Xiaoqing, Dai Jingxing, Ouyang Jun, Xiao Dan, Chang Yunbing
Department of Spine Surgery, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, Guangdong, China.
Guangdong Provincial Key Laboratory of Medical Biomechanics & Guangdong Engineering Research Center for Translation of Medical 3D Printing Application & National Virtual & Reality Experimental Education Center for Medical Morphology & National Experimental Education Demonstration Center for Basic Medical Sciences & National Key Discipline of Human Anatomy, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.
Heliyon. 2024 Jun 22;10(13):e33503. doi: 10.1016/j.heliyon.2024.e33503. eCollection 2024 Jul 15.
It is widely believed that the Percutaneous endoscopic lumbar discectomy (PELD) is associated with minimal blood loss. However, significant perioperative hidden blood loss (HBL) is frequently unaccounted for. This study aimed to investigate HBL and peri-operative factors contributing to HBL in a series of individuals undergoing PELD.
ology: A total of 156 consecutive patients with a mean age of 43.6 years (ranging from 18 to 80 years) who underwent PELD at our department from May 2019 to November 2020, were included in the study. Factors including gender, age, body mass index, symptom duration, operation approach/technique, operation duration, the presence of associated chronic diseases, and improvements in the Visual Analog Scale (VAS) score, Japanese Orthopaedic Association (JOA) score and the Oswestry Disability Index (ODI) were analyzed, and Gross's formula was applied to calculate blood loss, which was used to determine HBL.
The average total blood loss (TBL) was 221.0 ± 126.2 mL, while the average HBL was 181.7 ± 119.0 mL (82.2 % of TBL). There was no statistically significant difference in HBL between the transverse surgical approach and the interlayer approach. Additionally, no significant differences were observed in improvements in VAS, JOA, and ODI scores between the two surgical approaches. However, the multivariate linear regression analysis revealed that longer surgical time and foraminal decompression were factors contributing to the increase in HBL, which subsequently led to the occurrence of post-operative anemia.
HBL is significant in PELD cases with long surgical time and lumbar foraminal decompression.
人们普遍认为经皮内镜下腰椎间盘切除术(PELD)的失血量极少。然而,围手术期显著的隐性失血(HBL)常常未被计入。本研究旨在调查一系列接受PELD的患者的HBL情况以及导致HBL的围手术期因素。
本研究纳入了2019年5月至2020年11月在我科接受PELD的156例连续患者,平均年龄43.6岁(18至80岁)。分析了性别、年龄、体重指数、症状持续时间、手术入路/技术、手术时长、是否存在相关慢性病以及视觉模拟量表(VAS)评分、日本骨科协会(JOA)评分和奥斯维斯特残疾指数(ODI)的改善情况,并应用格罗斯公式计算失血量,以确定HBL。
平均总失血量(TBL)为221.0±126.2 mL,而平均HBL为181.7±119.0 mL(占TBL的82.2%)。横向手术入路和椎间孔入路之间的HBL无统计学显著差异。此外,两种手术入路在VAS、JOA和ODI评分改善方面也未观察到显著差异。然而,多因素线性回归分析显示,手术时间延长和椎间孔减压是导致HBL增加的因素,进而导致术后贫血的发生。
在手术时间长且进行腰椎椎间孔减压的PELD病例中,HBL显著。