Tarhini Ali, El Hasbani Georges, Farhat Lama, Ghieh Diamond, Uthman Imad
Faculty of Medicine, American University of Beirut, Beirut, Lebanon.
Department of Internal Medicine, St. Vincent's Medical Center Hartford HealthCare and Quinnipiac University, Bridgeport, CT, USA.
Clin Med Insights Arthritis Musculoskelet Disord. 2024 Jul 27;17:11795441241264823. doi: 10.1177/11795441241264823. eCollection 2024.
Idiopathic granulomatous mastitis (IGM) is an inflammatory-mediated rare disease that can be linked to rare manifestations. Erythema nodosum (EN) and polyarthritis, seen in a multitude of autoinflammatory and autoimmune diseases, have been rarely linked to IGM. Despite the cause of IGM being unclear, Corynebacterium infections are thought to play a role in the pathophysiology of IGM. Unusually, IGM has a relapsing and remitting course, which also applies to its systemic manifestations. As such, we present a case of IGM in a middle-aged lady who was initially thought to have Corynebacterium-containing unilateral abscesses for which drainage was performed. However, several abscesses devoid of bacterial growth started recurring, and the disease course was complicated by EN and polyarthritis. IGM, EN, and polyarthritis eventually resolved and were managed with symptomatic treatment.
特发性肉芽肿性乳腺炎（IGM）是一种由炎症介导的罕见疾病，可能与罕见表现相关。结节性红斑（EN）和多关节炎可见于多种自身炎症性和自身免疫性疾病，很少与IGM相关。尽管IGM的病因尚不清楚，但棒状杆菌感染被认为在IGM的病理生理学中起作用。不同寻常的是，IGM有复发和缓解的病程，这也适用于其全身表现。因此，我们报告一例中年女性IGM病例，该患者最初被认为患有含棒状杆菌的单侧脓肿并进行了引流。然而，几个无细菌生长的脓肿开始反复出现，病程并发EN和多关节炎。IGM、EN和多关节炎最终得以缓解，并采用对症治疗。
