Chabbouh Amel, Rebhi Faten, Ben Slimene Malek, Jaber Kahena, Dhaoui Abderaouf
Department of Dermatology, Military Hospital, Tunis, Tunisia.
Faculty of Medicine of Tunis, University of Tunis El Manar, Tunis, Tunisia.
Urol Case Rep. 2024 Jul 2;55:102789. doi: 10.1016/j.eucr.2024.102789. eCollection 2024 Jul.
Drug reaction with eosinophilia and systemic symptoms (DRESS)/drug-induced hypersensitivity syndrome (DIHS) is a life-threatening, multi-organ adverse drug reaction with a mortality rate of approximately 10 %-20 %. The most common culprit drugs are anticonvulsants, some antibiotics such as dapsone and minocycline, salazosulfapyridine, allopurinol and some antiretroviral molecules such as abacavir and nevirapine. Only one case of DRESS induced by sildenafil has been reported in the literature. Here we report a new case.
药物性嗜酸性粒细胞增多症及系统症状（DRESS）/药物性超敏反应综合征（DIHS）是一种危及生命的多器官药物不良反应，死亡率约为10%-20%。最常见的致病药物是抗惊厥药、一些抗生素（如氨苯砜和米诺环素）、柳氮磺胺吡啶、别嘌醇以及一些抗逆转录病毒分子（如阿巴卡韦和奈韦拉平）。文献中仅报道过1例由西地那非诱发的DRESS病例。在此，我们报告1例新病例。
