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全身麻醉下妇科手术后即刻出现化疗引起的周围神经病变短暂复发。

Transient recurrence of chemotherapy-induced peripheral neuropathy in the immediate postoperative period following gynaecological surgery under general anaesthesia.

作者信息

Ra O H, Tan J C, Zhao C W, Burns S L

机构信息

Brigham and Women's Hospital Boston USA.

出版信息

Anaesth Rep. 2024 Jul 25;12(2):e12315. doi: 10.1002/anr3.12315. eCollection 2024 Jul-Dec.

Abstract

Peripheral neuropathy is a well-described side effect of certain chemotherapeutic agents, including taxanes, and often improves in the weeks following treatment. The recurrence of motor and sensory neuropathies after anaesthesia has not yet been described to our knowledge. We present a case of transient recurrence of chemotherapy-induced peripheral neuropathy following general anaesthesia. Although an exact mechanism has not yet been described and is likely multifactorial in nature, anaesthetists should be prepared to address this phenomenon in the growing population of patients on chemotherapeutic agents.

摘要

周围神经病变是包括紫杉烷类在内的某些化疗药物所导致的一种广为人知的副作用,且常在治疗后的数周内有所改善。据我们所知,麻醉后运动和感觉神经病变的复发情况尚未见报道。我们报告一例全身麻醉后化疗引起的周围神经病变短暂复发的病例。尽管确切机制尚未阐明且可能具有多因素性质,但麻醉医生应准备好应对这一现象,因为使用化疗药物的患者群体在不断增加。

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Chemotherapy-induced peripheral neuropathy and rehabilitation: A review.化疗引起的周围神经病变与康复:综述
Semin Oncol. 2021 Jun;48(3):193-207. doi: 10.1053/j.seminoncol.2021.09.004. Epub 2021 Sep 22.
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Chemotherapy-Induced Peripheral Neuropathy.化疗引起的周围神经病变
JAMA Oncol. 2019 May 1;5(5):750. doi: 10.1001/jamaoncol.2018.6771.

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