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某属的化学成分、药理活性及质量评价方法:综述

Chemical constituents, pharmacological activities and quality evaluation methods of genus : A comprehensive review.

作者信息

Zhang Zhiyong, Zhang Xiaoyang, Wang Xi, Guo Xuting, Yan Xinhao, Li Zheng, Li Wenlong

机构信息

College of Pharmaceutical Engineering of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China.

State Key Laboratory of Component-based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China.

出版信息

Chin Herb Med. 2023 Aug 19;16(3):344-357. doi: 10.1016/j.chmed.2023.04.001. eCollection 2024 Jul.

Abstract

The genus is a multi-origin animal species with high medicinal and healthcare values. About 57 species of spread worldwide, of which about 14 species can be used as medicine, showing anti-oxidation, anti-inflammation, anti-depressant, anti-hypertension, anti-prostatic hyperplasia, antivirus, anti-apoptotic, antifatigue, and so on. And those pharmacological effects are mainly related to their active ingredients, including amino acids, abundant proteins (peptides and oligopeptides), fatty acids, nucleosides, steroids, and other small molecular compounds. The main means of authentication of species are morphological identification, microscopic identification, thin layer chromatography method, fingerprint method and genomics method. This review will provide useful insight for exploration, further study and precise medication of in the future.

摘要

该属是一种具有高药用和保健价值的多起源动物物种。约57种该属动物分布于世界各地,其中约14种可入药,具有抗氧化、抗炎、抗抑郁、抗高血压、抗前列腺增生、抗病毒、抗凋亡、抗疲劳等作用。而这些药理作用主要与其活性成分有关,包括氨基酸、丰富的蛋白质(肽和寡肽)、脂肪酸、核苷、类固醇以及其他小分子化合物。该属物种的主要鉴定方法有形态鉴定、显微鉴定、薄层色谱法、指纹图谱法和基因组学法。本综述将为该属动物未来的探索、进一步研究和精准用药提供有益的见解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7058/11283209/52ed00cbb300/gr1.jpg

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