次硫酸氢钠甲醛作为C1源：吲哚与芳基/烷基酰肼及亚磺酸盐的磺酰甲基化反应
Rongalite as a C1 Source: Sulfonylmethylation of Indoles with Aryl/Alkyl Hydrazides and Sulfinates.
作者信息
Kale Someshwar B, Patil Tejaswini A, Das Utpal
机构信息
Division of Organic Chemistry, CSIR-National Chemical Laboratory, Pune 411008, India.
Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India.
出版信息
J Org Chem. 2024 Aug 16;89(16):11347-11352. doi: 10.1021/acs.joc.4c01012. Epub 2024 Jul 29.
PMID:39072680
Abstract
Herein, we present a sulfonylmethylation of indoles with aryl/alkyl hydrazides and sulfinates that provides viable access to sulfone compounds using rongalite as a C1 source. This protocol features readily available chemicals and simple operations, and the products were obtained in moderate to good yields.
摘要
在此，我们报道了一种吲哚与芳基/烷基酰肼和亚磺酸盐的磺酰甲基化反应，该反应使用雕白粉作为C1源，为合成砜类化合物提供了可行的途径。该方法具有化学试剂易得、操作简单的特点，产物收率适中至良好。
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