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从一级预防到原始预防:值得这么做吗?

Going from Primary to Primordial Prevention: Is the Juice Worth the Squeeze?

机构信息

Department of Cardiology, Scripps Clinic, La Jolla, San Diego, CA, USA.

Department of Cardiology, United Medical Doctors, La Jolla, San Diego, CA, USA.

出版信息

Curr Cardiol Rep. 2024 Oct;26(10):1135-1143. doi: 10.1007/s11886-024-02109-3. Epub 2024 Jul 29.

Abstract

PURPOSE OF REVIEW

While primary prevention strategies target individuals who are at high risk of cardiovascular disease, there is rising interest towards primordial prevention that focuses on preventing the development of risk factors upstream of disease detection. Therefore, we review the advantages of primordial prevention interventions on minimizing future cardiovascular events.

RECENT FINDINGS

Primordial prevention of atherosclerotic cardiovascular disease involves behavioral, genetic, and environmental strategies, starting from fetal/infant health and continuing throughout childhood and young adulthood. Early interventions focusing on modifiable risk factors such as physical inactivity, non-ideal body weight, smoking, and environmental pollutants are important towards preventing the initial occurrence of risk factors such as hypertension, dyslipidemia, and diabetes to ultimately reduce cardiovascular disease. Implementing primordial prevention strategies early on in life can minimize cardiovascular events and lead to healthy aging in the population. Future studies can further evaluate the effectiveness of various primordial prevention strategies.

摘要

目的综述:虽然一级预防策略针对的是心血管疾病高危人群,但人们对一级预防的兴趣日益浓厚,一级预防侧重于在疾病检测之前就预防危险因素的发展。因此,我们综述了一级预防干预措施在最大限度减少未来心血管事件方面的优势。

最新发现:动脉粥样硬化性心血管疾病的一级预防包括从胎儿/婴儿健康开始并贯穿儿童和青年期的行为、遗传和环境策略。早期干预侧重于可改变的危险因素,如身体活动不足、非理想体重、吸烟和环境污染物,这对于预防高血压、血脂异常和糖尿病等危险因素的最初发生至关重要,从而最终降低心血管疾病的风险。在生命早期实施一级预防策略可以最大限度地减少心血管事件,并实现人群的健康老龄化。未来的研究可以进一步评估各种一级预防策略的有效性。

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