Department of Nursing, College of Nursing and Health Sciences, University of Massachusetts Boston, 100 Morrissey Blvd., Quinn Building-Second Floor, Boston, MA, 02125-3393, USA.
Division of Preventive & Behavioral Medicine, Department of Population & Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, MA, USA.
Curr Cardiol Rep. 2020 Jul 9;22(9):86. doi: 10.1007/s11886-020-01332-y.
Atherosclerotic-CVD processes begin early in life and are influenced over the life course by interaction of genetic and potential modifiable risk factors, behaviors, and environmental exposures. The purpose of this review is to highlight importance of primordial and primary prevention beginning early in the life course.
Evidence-based guidelines and recommendations for primordial and primary prevention support importance of individual/clinical and population-based approaches to CVD prevention beginning early in life with goal of reducing the risk and burden of CVD. Substantial evidence supports the individual and societal benefits of prevention of CVD and promotion of optimal cardiovascular health beginning early in life and extending across the life course and the need for additional research to guide and inform practices and policies enabling optimal cardiovascular health for all.
动脉粥样硬化性心血管疾病(CVD)的发生始于生命早期,其过程受到遗传因素和潜在可改变的风险因素、行为以及环境暴露之间相互作用的影响。本综述的目的是强调从生命早期开始进行一级和二级预防的重要性。
基于循证的一级和二级预防指南和建议支持在生命早期开始,通过个体/临床和人群为基础的方法来预防 CVD,目标是降低 CVD 的风险和负担。大量证据支持从生命早期开始预防 CVD 和促进最佳心血管健康,以及在整个生命过程中延续这一做法的个体和社会效益,并且需要进一步的研究来指导和告知实践和政策,使所有人都能获得最佳心血管健康。