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加拿大的结直肠癌的地域差异:综述。

Geographical Disparities in Colorectal Cancer in Canada: A Review.

机构信息

Shannon School of Business, Cape Breton University, Sydney, NS, Canada.

Faculty of Computer Science, Dalhousie University, Halifax, NS, Canada.

出版信息

Curr Oncol Rep. 2024 Oct;26(10):1249-1257. doi: 10.1007/s11912-024-01574-x. Epub 2024 Jul 29.

Abstract

PURPOSE OF REVIEW

Colorectal cancer (CRC) is a prominent contributor to cancer-related mortality in Canada. This review paper sheds light on the research conducted in Canada to scrutinize the influence of economicfactors. The review seeks to uncover notable disparities in Colorectal cancer incidence and mortality rate across diverse Canadian populations, including Indigenous communities, rural dwellers, and individuals with lower socioeconomic status (SES).

RECENT FINDINGS

Recent investigations reveal significant disparities in CRC incidence, mortality, and treatment outcomes among various demographic groups in Canada. Indigenous peoples, rural populations, and those with lower SES are particularly vulnerable to these disparities. Access to screening and specialized cancer care is notably limited for these marginalized populations, exacerbating existing health inequities. Furthermore, emerging evidence underscores the potential influence of dietary factors on CRC risk, highlighting the importance of tailored prevention and treatment strategies. The findings underscore the urgent need for targeted interventions aimed at enhancing access to CRC screening and specialized cancer care for disadvantaged populations in Canada. By addressing these disparities, more individuals can undergo timely screening and receive early-stage diagnoses, thereby improving prognosis and ultimately saving lives. However, to effectively bridge these gaps, further research is imperative to elucidate the underlying mechanisms driving these disparities and to identify and implement effective interventions.

摘要

目的综述

结直肠癌(CRC)是加拿大癌症相关死亡率的主要原因。本文综述了加拿大开展的研究,以仔细研究经济因素的影响。该综述旨在揭示加拿大不同人群中结直肠癌发病率和死亡率的显著差异,包括原住民社区、农村居民和社会经济地位较低的个体。

最近的发现

最近的调查显示,加拿大不同人群中 CRC 的发病率、死亡率和治疗结果存在显著差异。原住民、农村人口和社会经济地位较低的人群尤其容易受到这些差异的影响。这些边缘化人群接受筛查和专门癌症治疗的机会明显有限,加剧了现有的健康不平等。此外,新出现的证据强调了饮食因素对 CRC 风险的潜在影响,突出了制定针对特定人群的预防和治疗策略的重要性。这些发现强调了在加拿大针对弱势群体进行有针对性干预的迫切需要,以增强他们接受 CRC 筛查和专门癌症治疗的机会。通过解决这些差异,可以使更多的人能够及时进行筛查,并获得早期诊断,从而改善预后并最终挽救生命。然而,要有效缩小这些差距,就必须进行进一步的研究,以阐明导致这些差异的潜在机制,并确定和实施有效的干预措施。

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