Jiang Yifang, Tian Ruixin, Zhang Chi, Zhang Lujie, Cui Xiaoman, Wang Ping
Department of Respiratory Medicine, The Fourth Hospital of Hebei Medical University, Shijiazhuang, 050011, China.
Future Microbiol. 2024;19(14):1195-1202. doi: 10.1080/17460913.2024.2366653. Epub 2024 Jul 29.
Emergomycosis is a dimorphic fungal disease that is typically disseminated and fatal among immunocompromised individuals. In the case report, we presented a patient with intermittent fever, night sweats, coughing and phlegm. Chest computed tomography revealed multiple soft-tissue nodules in both lungs. Routine pathological and microbiological tests did not confirm the diagnosis. Therefore, we conducted pathogen detection using metagenomic next-generation sequencing in bronchoalveolar lavage fluid and identified the pulmonary infection caused by (). During the antifungal treatment, the patient experienced renal function damage, and we have attempted various antifungal drugs for treatment. Finally, the patient's condition was brought under control. Therefore, the metagenomic next-generation sequencing pathogen detection was essential.
播散性真菌病是一种双相真菌疾病,在免疫功能低下的个体中通常会播散并致死。在该病例报告中,我们介绍了一名有间歇性发热、盗汗、咳嗽和咳痰症状的患者。胸部计算机断层扫描显示双肺有多个软组织结节。常规病理和微生物学检查未确诊。因此,我们使用宏基因组下一代测序技术对支气管肺泡灌洗液进行病原体检测,并确定了由()引起的肺部感染。在抗真菌治疗过程中,患者出现肾功能损害,我们尝试了各种抗真菌药物进行治疗。最终,患者的病情得到控制。因此,宏基因组下一代测序病原体检测至关重要。