• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Reduction of disulfides by thioredoxin. Exceptional reactivity of insulin and suggested functions of thioredoxin in mechanism of hormone action.

作者信息

Holmgren A

出版信息

J Biol Chem. 1979 Sep 25;254(18):9113-9.

PMID:39074
Abstract
摘要

相似文献

1
Reduction of disulfides by thioredoxin. Exceptional reactivity of insulin and suggested functions of thioredoxin in mechanism of hormone action.硫氧还蛋白对二硫键的还原作用。胰岛素的特殊反应性以及硫氧还蛋白在激素作用机制中的推测功能。
J Biol Chem. 1979 Sep 25;254(18):9113-9.
2
Protein disulfide-isomerase is a substrate for thioredoxin reductase and has thioredoxin-like activity.蛋白质二硫键异构酶是硫氧还蛋白还原酶的底物，具有硫氧还蛋白样活性。
J Biol Chem. 1990 Jun 5;265(16):9114-20.
3
Thioredoxin catalyzes the reduction of insulin disulfides by dithiothreitol and dihydrolipoamide.硫氧还蛋白催化二硫苏糖醇和二氢硫辛酰胺对胰岛素二硫键的还原反应。
J Biol Chem. 1979 Oct 10;254(19):9627-32.
4
Human IgG is substrate for the thioredoxin system: differential cleavage pattern of interchain disulfide bridges in IgG subclasses.人免疫球蛋白G是硫氧还蛋白系统的底物：免疫球蛋白G亚类中链间二硫键的差异裂解模式。
Mol Immunol. 1997 Jul;34(10):709-17. doi: 10.1016/s0161-5890(97)00092-8.
5
Enzymatic reduction-oxidation of protein disulfides by thioredoxin.硫氧还蛋白对蛋白质二硫键的酶促还原-氧化反应
Methods Enzymol. 1984;107:295-300. doi: 10.1016/0076-6879(84)07019-1.
6
Enzyme reduction of disulfide bonds by thioredoxin. The reactivity of disulfide bonds in human choriogonadotropin and its subunits.
Eur J Biochem. 1976 Nov 15;70(2):377-83. doi: 10.1111/j.1432-1033.1976.tb11027.x.
7
Selenite is a substrate for calf thymus thioredoxin reductase and thioredoxin and elicits a large non-stoichiometric oxidation of NADPH in the presence of oxygen.亚硒酸盐是小牛胸腺硫氧还蛋白还原酶和硫氧还蛋白的底物，在有氧存在的情况下会引发大量非化学计量的NADPH氧化。
Eur J Biochem. 1992 Jul 15;207(2):435-39. doi: 10.1111/j.1432-1033.1992.tb17068.x.
8
Isolation and characterization of thioredoxin from the cyanobacterium, Anabaena sp.从蓝藻鱼腥藻中分离和鉴定硫氧还蛋白
J Biol Chem. 1981 Aug 25;256(16):8306-9.
9
Thioredoxin fragment 31-36 is reduced by dihydrolipoamide and reduces oxidized protein.硫氧还蛋白片段31 - 36被二氢硫辛酰胺还原，并能还原氧化型蛋白质。
Biochem Biophys Res Commun. 1988 Jan 15;150(1):156-62. doi: 10.1016/0006-291x(88)90499-8.
10
S-glutathiolated hepatocyte proteins and insulin disulfides as substrates for reduction by glutaredoxin, thioredoxin, protein disulfide isomerase, and glutathione.作为谷氧还蛋白、硫氧还蛋白、蛋白质二硫键异构酶和谷胱甘肽还原底物的S-谷胱甘肽化肝细胞蛋白和胰岛素二硫键
Arch Biochem Biophys. 1996 Nov 1;335(1):61-72. doi: 10.1006/abbi.1996.0482.

引用本文的文献

1
Thiamine disulfide derivatives in thiol redox regulation: Role of thioredoxin and glutathione systems.硫醇氧化还原调节中的二硫胺素衍生物：硫氧还蛋白和谷胱甘肽系统的作用。
Biofactors. 2025 Jan-Feb;51(1):e2121. doi: 10.1002/biof.2121. Epub 2024 Sep 20.
2
Enzymatic Studies Reveal pH and Temperature Sensitive Properties of the CLIC Proteins.酶学研究揭示了CLIC蛋白的pH值和温度敏感性特性。
Biomolecules. 2023 Sep 15;13(9):1394. doi: 10.3390/biom13091394.
3
Fluorescent Probes for Mammalian Thioredoxin Reductase: Mechanistic Analysis, Construction Strategies, and Future Perspectives.
用于哺乳动物硫氧还蛋白还原酶的荧光探针：机制分析、构建策略和未来展望。
Biosensors (Basel). 2023 Aug 13;13(8):811. doi: 10.3390/bios13080811.
4
Condensation of the β-cell secretory granule luminal cargoes pro/insulin and ICA512 RESP18 homology domain.β-细胞分泌颗粒腔内容物胰岛素原/胰岛素和 ICA512 RESP18 同源结构域的浓缩。
Protein Sci. 2023 Jun;32(6):e4649. doi: 10.1002/pro.4649.
5
OPDAylation of Thiols of the Redox Regulatory Network In Vitro.体外氧化还原调节网络硫醇的OPDA化作用
Antioxidants (Basel). 2022 Apr 27;11(5):855. doi: 10.3390/antiox11050855.
6
A Fluorescent Probe to Detect Quick Disulfide Reductase Activity in Bacteria.一种用于检测细菌中快速二硫键还原酶活性的荧光探针。
Antioxidants (Basel). 2022 Feb 13;11(2):377. doi: 10.3390/antiox11020377.
7
Can thiol-based redox systems be utilized as parts for synthetic biology applications?基于巯基的氧化还原系统可否被用作合成生物学应用的一部分？
Redox Rep. 2021 Dec;26(1):147-159. doi: 10.1080/13510002.2021.1966183.
8
Crystal structure of thioredoxin 1 from at 1.8 Å resolution shows unexpected plasticity of the loop preceding the catalytic site.来自[具体物种]的硫氧还蛋白1在1.8埃分辨率下的晶体结构显示，催化位点之前的环具有意想不到的可塑性。
Biochem Biophys Rep. 2020 Jan 24;21:100724. doi: 10.1016/j.bbrep.2019.100724. eCollection 2020 Mar.
9
The atypical thiol-disulfide exchange protein α-DsbA2 from Wolbachia pipientis is a homotrimeric disulfide isomerase.从沃尔巴克氏体中分离出的非典型硫醇-二硫键交换蛋白α-DsbA2 是一种三聚体二硫键异构酶。
Acta Crystallogr D Struct Biol. 2019 Mar 1;75(Pt 3):283-295. doi: 10.1107/S2059798318018442. Epub 2019 Feb 26.
10
Kinetic studies reveal a key role of a redox-active glutaredoxin in the evolution of the thiol-redox metabolism of trypanosomatid parasites.动力学研究揭示了一种氧化还原活性谷胱甘肽还原酶在鞭毛原生动物寄生虫硫醇氧化还原代谢进化中的关键作用。
J Biol Chem. 2019 Mar 1;294(9):3235-3248. doi: 10.1074/jbc.RA118.006366. Epub 2018 Dec 28.