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2019冠状病毒病大流行期间基本药物的可及性:一项关于肯尼亚经验和准备水平的定性研究

Availability of essential medicines during the COVID-19 pandemic: A qualitative study examining experiences and level of preparedness in Kenya.

作者信息

Onyango Joseph Odhiambo, Ogira Dosila, Kokwaro Gilbert

机构信息

Institute of Healthcare Management, Strathmore Business School, Strathmore University, Nairobi, Kenya.

出版信息

PLOS Glob Public Health. 2024 Jul 29;4(7):e0002547. doi: 10.1371/journal.pgph.0002547. eCollection 2024.

Abstract

This study examines the impact of the COVID-19 pandemic on the availability of essential medicines in Kenya and suggests actionable measures to enhance the country's preparedness for future pandemics. Utilising a cross-sectional qualitative design, the research combines a systematic review of the literature and 20 key informant interviews to provide a comprehensive analysis. The initial response to the pandemic involved resource reallocation, disrupting the procurement of essential medicines at national and county levels. Inefficiencies in these systems resulted in shortages and wastages of crucial medicines, exposing vulnerabilities in the health system. Furthermore, the study reveals regulatory policy weaknesses in Kenya, such as an inadequate legal framework for domestic pharmaceutical manufacturing and conflicting policies hindering medicine availability. The study recommends a multifaceted policy approach to ensure essential medicine availability during crises. Key recommendations include strengthening financial systems through increased government investments and innovative funding mechanisms, implementing price regulation policies, and enhancing the resilience of supply chain and procurement systems. Collaboration among various supply systems is essential to prevent stock-outs. Strengthening legislation and regulatory policies, increasing domestic pharmaceutical manufacturing capacity, and investing in health information systems are vital for sustained self-sufficiency and efficient service delivery. These comprehensive measures are essential to promote essential medicine availability, safeguard public health, and enhance resilience during crises.

摘要

本研究考察了新冠疫情对肯尼亚基本药物供应的影响,并提出了切实可行的措施,以加强该国对未来疫情的防范能力。该研究采用横断面定性设计,结合对文献的系统回顾和20次关键信息人访谈,以提供全面分析。对疫情的初步应对涉及资源重新分配,扰乱了国家和县级基本药物的采购。这些系统的低效导致关键药物短缺和浪费,暴露出卫生系统的脆弱性。此外,该研究揭示了肯尼亚监管政策的弱点,如国内药品生产的法律框架不足以及阻碍药品供应的相互冲突的政策。该研究建议采取多方面的政策方法,以确保危机期间基本药物的供应。主要建议包括通过增加政府投资和创新融资机制来加强金融系统、实施价格监管政策,以及增强供应链和采购系统的韧性。各种供应系统之间的合作对于防止缺货至关重要。加强立法和监管政策、提高国内药品生产能力以及投资于卫生信息系统对于实现持续自给自足和高效服务提供至关重要。这些全面措施对于促进基本药物供应、保障公众健康以及增强危机期间的韧性至关重要。

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