Berny Laure, Greffier Joël, Serrand Chris, Dabli Djamel, De Oliveira Fabien, de Forges Hélène, Beregi Jean-Paul, Frandon Julien
Department of medical imaging, CHU de Nîmes, université de Montpellier, Medical Imaging Group Nîmes, place du Pr.-Robert-Debré, 30029 Nîmes, France.
Department of biostatistics, clinical epidemiology, public health, and innovation in methodology (BESPIM), CHU de Nîmes, place du Pr.-Robert-Debré, 30029 Nîmes, France.
Res Diagn Interv Imaging. 2023 Mar 1;5:100025. doi: 10.1016/j.redii.2023.100025. eCollection 2023 Mar.
A nation-wide study recently published the dose reference levels for the main CT-guided interventional procedures in 5001 patients. We assessed the impact of patient's age, sex and targeted organ on the patient dose during thoracic and abdominopelvic biopsies and punctures/drainages.
Data were extracted from the previous nationwide study. All biopsies, punctures and drainages for thoracic or abdominopelvic locations performed between January 2017 and June 2019 in all participating centers were included in the study. Multivariable analyses were carried out using a linear regression of the dose-length product (DLP) log, adjusted to age, sex, anatomical location, number of helical acquisitions and inclusion center.
Of the 5001 patients of the initial study, 2383 benefited from thoracic or abdominopelvic procedures, including 674 percutaneous destructions excluded. 1709 patients (44 centers), 1045 men, 664 women, median age 64.4 ± 14.0 years were included. The mean DLP was 751.2 ± 642.7mGy.cm. It was significantly higher in men than women ( = 0.0005) and higher for abdominopelvic procedures than for thoracic locations (<0.0001).
Doses delivered to patients for abdominal and thoracic biopsies and punctures/drainages performed under CT guidance depend on gender and location. Furthers studies taking into account the patient's morphology and anatomical location of the procedure would allow proposing finer dose reference levels.
一项全国性研究最近公布了5001例患者主要CT引导介入手术的剂量参考水平。我们评估了患者年龄、性别和目标器官对胸部及腹部盆腔活检和穿刺/引流过程中患者剂量的影响。
数据取自先前的全国性研究。纳入2017年1月至2019年6月期间所有参与中心进行的所有胸部或腹部盆腔部位的活检、穿刺和引流。使用剂量长度乘积（DLP）对数的线性回归进行多变量分析，并根据年龄、性别、解剖位置、螺旋采集次数和纳入中心进行调整。
在初始研究的5001例患者中，2383例接受了胸部或腹部盆腔手术，其中674例经皮消融术被排除。纳入1709例患者（44个中心），其中男性1045例，女性664例，中位年龄64.4±14.0岁。平均DLP为751.2±642.7mGy.cm。男性的DLP显著高于女性（P = 0.0005），腹部盆腔手术的DLP高于胸部手术（P<0.0001）。
CT引导下进行的腹部和胸部活检及穿刺/引流所给予患者的剂量取决于性别和部位。进一步考虑患者形态和手术解剖位置的研究将有助于提出更精确的剂量参考水平。
