来自酵母（酿酒酵母）的天冬氨酸蛋白酶抑制剂IA3的作用选择性。
The selectivity of action of the aspartic-proteinase inhibitor IA3 from yeast (Saccharomyces cerevisiae).
作者信息
Dreyer T, Valler M J, Kay J, Charlton P, Dunn B M
出版信息
Biochem J. 1985 Nov 1;231(3):777-9. doi: 10.1042/bj2310777.
Abstract
The ability of the aspartic-proteinase inhibitor IA3 from yeast (Saccharomyces cerevisiae) to affect the activities of a range of mammalian and microbial aspartic proteinases was examined. The inhibitor appeared to be completely selective in that only the aspartic proteinase A from yeast was inhibited to any significant extent. IA3 thus represents the first example of a totally specific, naturally occurring, aspartic-proteinase inhibitor.
摘要
研究了来自酵母（酿酒酵母）的天冬氨酸蛋白酶抑制剂IA3对一系列哺乳动物和微生物天冬氨酸蛋白酶活性的影响。该抑制剂似乎具有完全的选择性，因为只有来自酵母的天冬氨酸蛋白酶A受到了显著抑制。因此，IA3是完全特异性的天然存在的天冬氨酸蛋白酶抑制剂的首个实例。
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