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射血分数保留的心力衰竭前期的发展与挑战

Development and Challenges of Pre-Heart Failure with Preserved Ejection Fraction.

作者信息

Dong Guoju

机构信息

Department of Cardiovascular Internal Medicine, Xiyuan Hospital, Chinese Academy of Traditional Chinese Medicine, 100091 Beijing, China.

National Clinical Research Center for Chinese Medicine Cardiology, Xiyuan Hospital, Chinese Academy of Traditional Chinese Medicine, 100091 Beijing, China.

出版信息

Rev Cardiovasc Med. 2023 Sep 25;24(9):274. doi: 10.31083/j.rcm2409274. eCollection 2023 Sep.

DOI:10.31083/j.rcm2409274
PMID:39076392
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11270127/
Abstract

Pre-heart failure with preserved ejection fraction (Pre-HFpEF) is a critical link to the development of heart failure with preserved ejection fraction (HFpEF). Early recognition and early intervention of pre-HFpEF will halt the progression of HFpEF. This article addresses the concept proposal, development, and evolution of pre-HFpEF, the mechanisms and risks of pre-HFpEF, the screening methods to recognize pre-HFpEF, and the treatment of pre-HFpEF. Despite the challenges, we believe more focus on the topic will resolve more problems.

摘要

射血分数保留的心力衰竭前期(Pre-HFpEF)是射血分数保留的心力衰竭(HFpEF)发展的关键环节。对Pre-HFpEF进行早期识别和早期干预将阻止HFpEF的进展。本文阐述了Pre-HFpEF的概念提出、发展及演变、Pre-HFpEF的机制和风险、识别Pre-HFpEF的筛查方法以及Pre-HFpEF的治疗。尽管存在挑战,但我们相信对该主题给予更多关注将解决更多问题。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/757d/11270127/0cfcc9353adc/2153-8174-24-9-274-g2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/757d/11270127/5099b05ec72a/2153-8174-24-9-274-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/757d/11270127/0cfcc9353adc/2153-8174-24-9-274-g2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/757d/11270127/5099b05ec72a/2153-8174-24-9-274-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/757d/11270127/0cfcc9353adc/2153-8174-24-9-274-g2.jpg

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本文引用的文献

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Effect of Sacubitril/Valsartan vs Valsartan on Left Atrial Volume in Patients With Pre-Heart Failure With Preserved Ejection Fraction: The PARABLE Randomized Clinical Trial.沙库巴曲缬沙坦对比缬沙坦对射血分数保留的心力衰竭前期患者左心房容积的影响:PARABLE 随机临床试验。
JAMA Cardiol. 2023 Apr 1;8(4):366-375. doi: 10.1001/jamacardio.2023.0065.
2
Genetic causes of heart failure with preserved ejection fraction: emerging pharmacological treatments.射血分数保留的心力衰竭的遗传病因:新出现的药物治疗方法
Eur Heart J. 2023 Feb 21;44(8):656-667. doi: 10.1093/eurheartj/ehac764.
3
A Simple Score to Identify Increased Risk of Transthyretin Amyloid Cardiomyopathy in Heart Failure With Preserved Ejection Fraction.
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JAMA Cardiol. 2022 Oct 1;7(10):1036-1044. doi: 10.1001/jamacardio.2022.1781.
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Cardiac magnetic resonance identifies raised left ventricular filling pressure: prognostic implications.心脏磁共振识别左心室充盈压升高:预后意义。
Eur Heart J. 2022 Jul 7;43(26):2511-2522. doi: 10.1093/eurheartj/ehac207.
5
Clinical Implications of Plasma Galectin-3 in Heart Failure With Preserved Ejection Fraction: A Meta-Analysis.射血分数保留的心力衰竭患者血浆半乳糖凝集素-3的临床意义:一项荟萃分析
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