Robles Antonio Gianluca, Palamà Zefferino, Scarà Antonio, Borrelli Alessio, Gianfrancesco Domenico, Bartolomucci Francesco, Nesti Martina, Cavarretta Elena, De Masi De Luca Gabriele, Romano Silvio, Sciarra Luigi
Department of Life, Health and Environmental Sciences, University of L'Aquila, 67100 L'Aquila, Italy.
Cardiology Department, Ospedale "L. Bonomo", 76123 Andria, Italy.
Rev Cardiovasc Med. 2024 Apr 8;25(4):140. doi: 10.31083/j.rcm2504140. eCollection 2024 Apr.
Pulmonary vein isolation (PVI) is the established cornerstone for atrial fibrillation (AF) ablation, indeed current guidelines recognize PVI as the gold standard for first-time AF ablation, regardless of if it is paroxysmal or persistent. Since 1998 when Haïssaguerre pioneered AF ablation demonstrating a burden reduction after segmental pulmonary vein (PV) ablation, our approach to PVI was superior in terms of methodology and technology. This review aims to describe how paroxysmal atrial fibrillation ablation has evolved over the last twenty years. We will focus on available techniques, a mechanistic understanding of paroxysmal AF genesis and the possibility of a tailored approach for the treatment of AF, before concluding with a future perspective.
肺静脉隔离（PVI）是心房颤动（AF）消融的既定基石，实际上，当前指南将PVI视为首次AF消融的金标准，无论其为阵发性还是持续性。自1998年Haïssaguerre率先进行AF消融并证明节段性肺静脉（PV）消融后负担减轻以来，我们的PVI方法在方法和技术方面更具优势。本综述旨在描述阵发性心房颤动消融在过去二十年中的发展历程。在得出未来展望之前，我们将重点关注可用技术、对阵发性AF发生机制的理解以及AF治疗的个性化方法的可能性。
