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新型心脏植入式设备感染的新观念

Emerging Concepts on Infection of Novel Cardiac Implantable Devices.

作者信息

Ramadan Mohammad Said, Gallo Raffaella, Patauner Fabian, Bertolino Lorenzo, Durante-Mangoni Emanuele

机构信息

Department of Precision Medicine, University of Campania 'L. Vanvitelli' Napoli, Italy and Unit of Infectious and Transplant Medicine, AORN Ospedali dei Colli-Monaldi Hospital, 80131 Napoli, Italy.

出版信息

Rev Cardiovasc Med. 2022 Aug 5;23(8):277. doi: 10.31083/j.rcm2308277. eCollection 2022 Aug.

DOI:10.31083/j.rcm2308277
PMID:39076625
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11266971/
Abstract

Novel cardiac devices, including the MitraClip system, occluder devices, leadless pacemakers, and subcutaneous implantable cardioverter defibrillators (S-ICD), are mostly used in the management of patients who are at high risk for surgery and/or developing infections. Several mechanisms render most of these devices resistant to infection, including avoiding long transvenous access and novel manufacturing material. Since subjects who use these devices already endure several comorbid conditions, uncommon cases of device-associated infection could result in serious complications and increased mortality. In this review, we aim to summarize the current state of evidence on the incidence, clinical presentation, management, and prognosis of new cardiac devices' associated infection.

摘要

新型心脏设备,包括二尖瓣夹合系统、封堵器、无导线起搏器和皮下植入式心律转复除颤器(S-ICD),主要用于治疗手术风险高和/或有感染风险的患者。这些设备大多通过多种机制来抵抗感染,包括避免长时间经静脉通路以及使用新型制造材料。由于使用这些设备的患者已经患有多种合并症,罕见的与设备相关的感染病例可能会导致严重并发症并增加死亡率。在本综述中,我们旨在总结有关新型心脏设备相关感染的发生率、临床表现、管理和预后的现有证据状况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dcbf/11266971/a3fdeeafed2b/2153-8174-23-8-277-g2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dcbf/11266971/f6640f538fa5/2153-8174-23-8-277-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dcbf/11266971/a3fdeeafed2b/2153-8174-23-8-277-g2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dcbf/11266971/f6640f538fa5/2153-8174-23-8-277-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dcbf/11266971/a3fdeeafed2b/2153-8174-23-8-277-g2.jpg

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本文引用的文献

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The development of the extravascular defibrillator with substernal lead placement: A new Frontier for device-based treatment of sudden cardiac arrest.经胸骨下心外膜导联除颤器的发展:基于器械治疗心搏骤停的新前沿。
J Cardiovasc Electrophysiol. 2022 Jun;33(6):1085-1095. doi: 10.1111/jce.15511. Epub 2022 May 8.
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Atrial shunt device for heart failure with preserved and mildly reduced ejection fraction (REDUCE LAP-HF II): a randomised, multicentre, blinded, sham-controlled trial.用于射血分数保留和轻度降低的心力衰竭的心房分流装置(REDUCE LAP-HF II):一项随机、多中心、双盲、假对照试验。
Lancet. 2022 Mar 19;399(10330):1130-1140. doi: 10.1016/S0140-6736(22)00016-2. Epub 2022 Feb 1.
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Endothelialization of Amplatzer PFO Occluder Device 12 Months After Implantation: First-in-Human Angioscopic Assessment.
Amplatzer PFO 封堵器植入 12 个月后的内皮化:首例人体血管内镜评估。
J Invasive Cardiol. 2022 Feb;34(2):E151. doi: 10.25270/jic/21.00305.
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Clinical Outcomes of Non-Atrial Fibrillation Bradyarrhythmias Treated With a Ventricular Demand Leadless Pacemaker Compared With an Atrioventricular Synchronous Transvenous Pacemaker - A Propensity Score-Matched Analysis.与房室同步经静脉起搏器相比,使用心室按需无导线起搏器治疗非心房颤动缓慢性心律失常的临床结果 - 倾向评分匹配分析。
Circ J. 2022 Jul 25;86(8):1283-1291. doi: 10.1253/circj.CJ-21-0889. Epub 2022 Jan 29.
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Heart Disease and Stroke Statistics-2022 Update: A Report From the American Heart Association.《心脏病与卒中统计-2022 更新:美国心脏协会报告》。
Circulation. 2022 Feb 22;145(8):e153-e639. doi: 10.1161/CIR.0000000000001052. Epub 2022 Jan 26.
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J Cardiovasc Electrophysiol. 2022 Mar;33(3):471-472. doi: 10.1111/jce.15366. Epub 2022 Jan 31.
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