Nie Lei, Xiang Xuying, Wen Cheng, Zhang Feng, Xia Yuanpeng, Wang Yong, Mao Ling
Department of Neurology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 430022 Wuhan, Hubei, China.
Rev Cardiovasc Med. 2023 May 5;24(5):139. doi: 10.31083/j.rcm2405139. eCollection 2023 May.
Atherosclerosis (AS) is a long-standing cardiovascular and cerebrovascular disease. Its occurrence and development are related to the pathophysiology of lipids including cholesteryl ester (CE), cholesterol, triacylglycerol (TG), and phospholipid (PL). In this review, we focus on the roles and possible mechanisms of different lipid subcomponents in the process of AS, and provide new ideas for the prevention, diagnosis and treatment of AS.
动脉粥样硬化(AS)是一种长期的心血管和脑血管疾病。其发生和发展与包括胆固醇酯(CE)、胆固醇、甘油三酯(TG)和磷脂(PL)在内的脂质病理生理学有关。在本综述中,我们重点关注不同脂质亚组分在AS过程中的作用及可能机制,并为AS的预防、诊断和治疗提供新思路。