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胎儿颅内出血的产前超声诊断及产后结局:两例病例报告

Prenatal sonographic diagnosis and postnatal outcomes of fetal intracranial hemorrhage: Two case report.

作者信息

Yen Vu T H

机构信息

Department of Radiology, Diamond Healthcare center, Ho Chi Minh city, Vietnam.

出版信息

Radiol Case Rep. 2024 Jul 13;19(9):4066-4072. doi: 10.1016/j.radcr.2024.06.035. eCollection 2024 Sep.

Abstract

Intracranial hemorrhage (ICH) in pregnancy, estimated at 1 in 10,000 cases, presents significant diagnostic challenges prenatally despite advanced imaging techniques such as ultrasonography (US) and magnetic resonance imaging (MRI). Detecting ICH is crucial for pregnancy management and future treatment decisions aimed at improving fetal survival and reducing brain damage. This report presents the diagnosis and outcomes of 2 cases of prenatal ICH. The first case involves a 30-year-old pregnant woman with irregular prenatal care diagnosed with ICH at 32 weeks of gestation via US and MRI. She chose to continue the pregnancy, delivering a 3160 g male infant at 36 weeks via cesarean section. Following NICU care including resuscitation and ventriculoperitoneal shunt placement, the infant was discharged. Subsequent examinations showed a reduction in ventricle size. In the second case, a 27-year-old woman taking acenocoumarol for a mechanical heart valve developed fetal subdural hemorrhage detected by US and MRI. She opted to terminate the pregnancy, resulting in a stillborn male infant weighing 1530 g. Fetal ICH presents with varying severity and prognostic implications, diagnosed and graded using US. Fetal cranial MRI may help clarify the etiology. Management remains controversial, with termination of pregnancy potentially warranted in severe cases due to poor prognosis. Further research is needed to refine management and improve outcomes in fetal ICH.

摘要

妊娠期颅内出血(ICH)的发生率估计为万分之一,尽管有超声检查(US)和磁共振成像(MRI)等先进的成像技术,但产前诊断仍面临重大挑战。检测ICH对于妊娠管理以及旨在提高胎儿存活率和减少脑损伤的未来治疗决策至关重要。本报告介绍了2例产前ICH的诊断及结果。第一例是一名30岁的孕妇,产前检查不规律,在妊娠32周时通过超声和MRI诊断为ICH。她选择继续妊娠,在36周时通过剖宫产分娩出一名3160克的男婴。经过包括复苏和脑室腹腔分流术在内的新生儿重症监护病房护理后,婴儿出院。随后的检查显示脑室大小缩小。第二例是一名27岁的女性,因机械心脏瓣膜服用醋硝香豆素,通过超声和MRI检测出胎儿硬膜下出血。她选择终止妊娠,产下一名体重1530克的死产男婴。胎儿ICH的严重程度和预后影响各不相同,可通过超声进行诊断和分级。胎儿头颅MRI可能有助于明确病因。治疗仍存在争议,由于预后不良,严重病例可能需要终止妊娠。需要进一步研究以完善胎儿ICH的治疗并改善其预后。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fcc0/11284951/33ef12b729bd/gr1.jpg

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