Kuo Deng-Yu, Wu Yen-Wen, Hsieh Chen-Hsi, Liao Li-Jen, Shueng Pei-Wei
Division of Radiation Oncology, Department of Radiology, Far Eastern Memorial Hospital, 220 New Taipei, Taiwan.
Division of Cardiology, Cardiovascular Medical Center, Far Eastern Memorial Hospital, 220 New Taipei, Taiwan.
Rev Cardiovasc Med. 2022 Jun 27;23(7):240. doi: 10.31083/j.rcm2307240. eCollection 2022 Jul.
Head and neck cancer (HNC) shares some risk factors with cardiovascular disease. Neck radiotherapy (RT) causes carotid artery injury and stenosis. In HNC patients treated with RT, the prevalence rate of severe ( 70%) carotid artery stenosis is 10%, and the cumulative incidence continuously increases over time. There is at least a two-fold risk of cerebrovascular events in these patients compared with the normal population. Carotid artery stenosis is mainly assessed and diagnosed via duplex ultrasonography. Angioplasty and stenting may be recommended to patients who developed severe post-irradiation carotid artery stenosis. This review assessed Taiwanese data that provided some recommendations for HNC patients treated with RT. With consideration of the high prevalence rate of carotid artery stenosis after neck irradiation, duplex ultrasonography should be included in the follow-up workup.
头颈癌（HNC）与心血管疾病有一些共同的风险因素。颈部放疗（RT）会导致颈动脉损伤和狭窄。在接受放疗的HNC患者中，重度（≥70%）颈动脉狭窄的患病率为10%，且累积发病率随时间持续增加。与正常人群相比，这些患者发生脑血管事件的风险至少高出两倍。颈动脉狭窄主要通过双功超声进行评估和诊断。对于发生严重放疗后颈动脉狭窄的患者，可能会建议进行血管成形术和支架置入术。本综述评估了台湾的数据，为接受放疗的HNC患者提供了一些建议。考虑到颈部放疗后颈动脉狭窄的高患病率，双功超声应纳入随访检查。
