Haimovici H
J Cardiovasc Surg (Torino). 1979 Jul-Aug;20(4):349-57.
Metabolic complications secondary to acute arterial occlusions occurred in 7.5% of our cases. It is pointed out that the characteristic biochemical changes: 1) may already be detectable during the ischemic phase, and 2) are more pronounced after revascularization of the extremity. Their identification at the early stage is essential for preventing the serious outcome of the late stage. Amputation rates are quite high (40-50%) and mortality rates are similarly great (30-80%). The ischemic rhabdomyolysis which leads to the clinical and manifestations and biochemical alterations is the initiating pathogenic factor of this syndrome. Prophylaxis and management of these complications were reviewed.
我们的病例中，急性动脉闭塞继发的代谢并发症发生率为7.5%。需要指出的是，其特征性生化变化：1）在缺血期可能已可检测到，2）在肢体血运重建后更为明显。早期识别这些变化对于预防晚期严重后果至关重要。截肢率相当高（40%-50%），死亡率同样很高（30%-80%）。导致临床症状、体征及生化改变的缺血性横纹肌溶解是该综合征的起始致病因素。本文对这些并发症的预防和处理进行了综述。
