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[前列腺癌:骨闪烁显像的价值。观点]

[Cancer of the prostate: value of bone scintigraphy. Point of view].

作者信息

Lumbroso J, Guermazi F, Wibault P, Henry-Amar M, Travagli J P

出版信息

Bull Cancer. 1985;72(5):436-41.

PMID:3907735
Abstract

Radionuclide bone scanning carried out with technetium radiopharmaceutics detects almost all prostatic carcinoma osseous metastases. It is easy to recognize focal areas of increased tracer uptake or a diffuse increased uptake, and the test provides a synthetic view of the entire skeleton. Complementary bone radiographs are necessary if the diagnosis remains doubtful, if mechanical complications are searched and if there is a post-radiotherapeutic decrease of the tracer uptake. A bone scan is necessary before the radical treatment of the primary tumour, in order to rule out the possibility of bone metastases. The initial bone scan has also a pronostic value. However, in the follow-up of initially non-metastatic patients, serial bone scans should not be realized when clinical symptoms or biological abnormalities lack. Bone scintigraphy is also useful to monitor the course of bone metastases under treatment, especially when the value of new therapeutic agents is investigated.

摘要

用锝放射性药物进行的放射性核素骨扫描几乎能检测出所有前列腺癌骨转移。很容易识别放射性示踪剂摄取增加的局灶性区域或弥漫性摄取增加,该检查能提供整个骨骼的综合影像。如果诊断仍存疑问、寻找机械性并发症或存在放疗后示踪剂摄取减少的情况,则需要补充骨X光片。在对原发肿瘤进行根治性治疗之前,必须进行骨扫描,以排除骨转移的可能性。初始骨扫描也具有预后价值。然而,在对最初无转移的患者进行随访时,如果没有临床症状或生物学异常,则不应进行系列骨扫描。骨闪烁显像对于监测治疗中骨转移的进程也很有用,尤其是在研究新治疗药物的效果时。

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