Elefteriades John A
Aortic Institute at Yale-New Haven Hospital, Yale University School of Medicine, New Haven, CT 06510, USA.
Rev Cardiovasc Med. 2022 Apr 28;23(5):159. doi: 10.31083/j.rcm2305159. eCollection 2022 May.
This article reviews the concept and extensive experimentation done over two decades ago to convert and apply skeletal muscle for cardiac assistance-so called "cardiomyoplasty". Skeletal muscle was either wrapped around a failing heart or fashioned into accessory cardiac pumping chambers. Although the era of cardiomyoplasty came to an end when the cardiac wraps were found ineffective, the concept of independent accessory skeletal muscle ventricles may be worth another look.
本文回顾了二十多年前为实现骨骼肌转化并应用于心脏辅助（即所谓的“心肌成形术”）所进行的概念研究和广泛实验。骨骼肌要么被包裹在衰竭的心脏周围，要么被制作为辅助性心脏泵血腔室。尽管当发现心脏包裹术无效时，心肌成形术时代就此结束，但独立的辅助性骨骼肌心室这一概念或许值得重新审视。
