Letsou G V, Austin L, Grandjean P A, Braxton J H, Elefteriades J A
Department of Surgery, Yale University School of Medicine, New Haven, CT 06510, USA.
Cardiol Clin. 1995 Feb;13(1):121-4.
Dynamic cardiomyoplasty is a promising new technique that appears to effect symptomatic improvement in patients with NYHA class III heart failure. Objective improvement in systolic performance of the left ventricle appears small but remains to be further defined. No survival advantage has yet been realized, although this may be seen as the technique is further refined and operative risk curtailed. Mechanism of action may include a girdling effect that prevents progressive left ventricular dilatation. This effect may be independent of any role in augmenting systolic performance. Randomized clinical trials currently in progress will provide definitive answers within the next few years to these important questions.
动力性心肌成形术是一项很有前景的新技术，似乎能使纽约心脏协会（NYHA）心功能III级的心力衰竭患者症状得到改善。左心室收缩功能的客观改善似乎不大，但仍有待进一步明确。目前尚未观察到生存优势，不过随着该技术的进一步完善和手术风险的降低，可能会出现生存优势。其作用机制可能包括一种环束效应，可防止左心室进行性扩张。这种效应可能与增强收缩功能的任何作用无关。目前正在进行的随机临床试验将在未来几年内为这些重要问题提供明确答案。
