Takahashi Yoshihide
The Department of Cardiovascular Medicine, Shin-Yurigaoka General Hospital, 215-0026 Kawasaki, Japan.
Rev Cardiovasc Med. 2024 Jan 15;25(1):26. doi: 10.31083/j.rcm2501026. eCollection 2024 Jan.
Understanding the initiating role of pulmonary veins in atrial fibrillation (AF) has led to the development of pulmonary vein isolation (PVI). The efficacy of PVI is high for paroxysmal AF, whereas it is limited for non-paroxysmal AF. This fact highlights the necessity of understanding the mechanism through which AF is maintained, to develop ablation strategies that would be required in addition to the PVI. Mapping AF in animal models and humans has led to the identification of focal or rotational drivers. New technologies have been developed to identify those AF drivers and are used as a guide for catheter ablation. This review article aims to provide a comprehensive overview of the current state of knowledge regarding AF drivers and the various mapping approaches used to identify them.
认识到肺静脉在心房颤动（AF）中的起始作用，促使了肺静脉隔离（PVI）技术的发展。PVI对阵发性AF的疗效很高，而对非阵发性AF的疗效有限。这一事实凸显了了解AF维持机制的必要性，以便开发除PVI之外还需要的消融策略。在动物模型和人类中对AF进行标测，已导致识别出局灶性或旋转性驱动因素。已开发出新技术来识别那些AF驱动因素，并将其用作导管消融的指导。这篇综述文章旨在全面概述有关AF驱动因素的当前知识状态以及用于识别它们的各种标测方法。
