Hospital Universitario Lucus Augusti, Lugo, España.
Complejo Hospitalario Universitario de Santiago de Compostela, Santiago de Compostela, España.
Rev Neurol. 2024 Aug 16;79(4):107-113. doi: 10.33588/rn.7904.2024175.
The relationship between epilepsy and music is poorly understood. Musicogenic epilepsy, which involves seizures triggered by music, and epilepsy that triggers or involves musical experiences are rare. Anti-seizure medications (ASMs) may affect cognition and possibly the musical sphere. The relationship between epilepsy, ASMs and music perception is insufficiently investigated in the literature. This study describes the clinical characteristics of patients with epilepsy with advanced musical knowledge, and aims to understand the disease's involvement in the musical sphere.
A qualitative study was conducted in epileptic patients with musical knowledge, investigating their musical perception before and after a diagnosis of epilepsy and after a change of ASM when this was possible. Questionnaires and recordings of music were used to assess musical perception.
Fourteen patients had musical knowledge, and the majority of these (50%) had temporal lobe epilepsy. A total of 92.8% of the patients stated that epilepsy or its medications had affected them in the musical sphere. There was no clear relationship between the lateralisation of the epilepsy and musical involvement. 42.9% were professional musicians, and had to give up their profession. The patients prescribed with more than one ASM had greater musical involvement.
Temporal lobe epilepsy appears to have the greatest effect on music perception, and more studies with ASM and music perception are needed to determine its effects.
癫痫与音乐之间的关系尚未被充分理解。音乐性癫痫是指由音乐引发的癫痫发作，而癫痫发作或涉及音乐体验则较为罕见。抗癫痫药物（ASM）可能会影响认知能力，甚至可能影响音乐领域。文献中对癫痫、ASM 和音乐感知之间的关系研究不足。本研究描述了具有高级音乐知识的癫痫患者的临床特征，旨在了解该疾病对音乐领域的影响。
对具有音乐知识的癫痫患者进行了一项定性研究，调查了他们在癫痫诊断前后以及在可能的情况下改变 ASM 后对音乐的感知。使用问卷和音乐录音来评估音乐感知。
共有 14 名患者具有音乐知识，其中大多数（50%）患有颞叶癫痫。共有 92.8%的患者表示癫痫或其药物治疗在音乐领域对他们产生了影响。癫痫的侧化与音乐参与之间没有明确的关系。42.9%的患者是专业音乐家，不得不放弃他们的职业。服用一种以上 ASM 的患者的音乐参与度更高。
颞叶癫痫似乎对音乐感知的影响最大，需要更多关于 ASM 和音乐感知的研究来确定其影响。
