Memon Roomia, Niazi Javed H, Qureshi Anjum
Sabanci University, SUNUM Nanotechnology Research and Application Center, Orta Mah. Tuzla 34956, Istanbul, Turkey.
Nanoscale. 2024 Aug 22;16(33):15419-15445. doi: 10.1039/d4nr01175a.
The excessive presence of airborne fungal spores presents major concerns with potential adverse impacts on public health and food safety. These spores are recognized as pathogens and allergens prevalent in both outdoor and indoor environments, particularly in public spaces such as hospitals, schools, offices and hotels. Indoor environments pose a heightened risk of pulmonary diseases due to continuous exposure to airborne fungal spore particles through constant inhalation, especially in those individuals with weakened immunity and immunocompromised conditions. Detection methods for airborne fungal spores are often expensive, time-consuming, and lack sensitivity, making them unsuitable for indoor/outdoor monitoring. However, the emergence of micro-nano biosensor systems offers promising solutions with miniaturized designs, nanomaterial integration, and microfluidic systems. This review provides a comprehensive overview of recent advancements in bio-nano-sensor system technology for detecting airborne fungal spores, while also discussing future trends in biosensor device development aimed at achieving rapid and selective identification of pathogenic airborne fungi.
空气中真菌孢子的过量存在引发了对公共卫生和食品安全潜在不利影响的重大担忧。这些孢子被认为是在室外和室内环境中普遍存在的病原体和过敏原，尤其是在医院、学校、办公室和酒店等公共场所。由于通过持续吸入不断接触空气中的真菌孢子颗粒，室内环境对肺部疾病构成了更高的风险，特别是对于免疫力较弱和免疫功能低下的个体。空气中真菌孢子的检测方法通常昂贵、耗时且缺乏灵敏度，使其不适用于室内/室外监测。然而，微纳生物传感器系统的出现提供了具有小型化设计、纳米材料集成和微流控系统的有前景的解决方案。本文综述了用于检测空气中真菌孢子的生物纳米传感器系统技术的最新进展，同时还讨论了生物传感器设备开发的未来趋势，旨在实现对致病性空气传播真菌的快速和选择性识别。
