Department of Urology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Department of Urology, University of Miami Miller School of Medicine, Miami, Florida, USA.
J Endourol. 2024 Sep;38(9):929-935. doi: 10.1089/end.2023.0688. Epub 2024 Aug 13.
Percutaneous nephrolithotomy (PCNL) remains the gold standard treatment for patients with complete staghorn stones, for which multiple access tracts may be required. In this study, we describe a series of patients undergoing PCNL with a minimum of five dilated access tracts. We performed a multi-institutional retrospective review of 10 patients with complete staghorn stones who underwent PCNL requiring five or more access tracts. We recorded patient demographics, stone characteristics postoperative complications, and stone-free rates (SFRs). The primary endpoint was any postoperative complication. Secondary endpoints included SFR, operative time, and length of stay. SFR was defined as absence of stones or residual fragments <4 mm. A total of 10 patients from two institutions were included. Access tract number ranged from 5 to 11, and median stone volume was 233,042 mm. Seven patients (70%) experienced postoperative complications, ranging from Clavien II to IVa. Three patients (30%) required blood transfusions. Median operative time was 312 minutes ranging from 180 to 560 minutes. Five patients (50%) were stone-free after the initial procedure. Of those with residual fragments, 4 (40%) required reoperation to be rendered stone-free. Median length of stay was 2.5 days, with a range of 1-6 days. To our knowledge, this is the largest series of patients undergoing PCNL with five or more access tracts reported to date. This study confirms that PCNL with five or more tracts is feasible and relatively safe, albeit with a high rate of complications in the immediate postoperative period.
经皮肾镜碎石术(PCNL)仍然是鹿角形结石患者的金标准治疗方法,可能需要多个通道。在这项研究中,我们描述了一组接受至少 5 个扩张通道的 PCNL 治疗的患者。我们对两家机构的 10 例接受 PCNL 治疗、需要 5 个或更多通道的完全鹿角形结石患者进行了多机构回顾性分析。我们记录了患者的人口统计学特征、结石特征、术后并发症和结石清除率(SFR)。主要终点是任何术后并发症。次要终点包括 SFR、手术时间和住院时间。SFR 定义为无结石或残留碎片<4mm。共纳入 2 家机构的 10 例患者。通道数量为 5 至 11 个,中位结石体积为 233042mm。7 例患者(70%)发生术后并发症,从 Clavien II 级到 IVa 级不等。3 例患者(30%)需要输血。中位手术时间为 312 分钟,范围为 180 至 560 分钟。5 例患者(50%)在初始手术后无结石。残留碎片的患者中,4 例(40%)需要再次手术才能清除结石。中位住院时间为 2.5 天,范围为 1-6 天。据我们所知,这是迄今为止报道的接受 5 个或更多通道 PCNL 治疗的最大系列患者。本研究证实,5 个或更多通道的 PCNL 是可行且相对安全的,尽管在术后早期并发症发生率较高。