Oei L S, Thompson J S, Corry R J
Transplantation. 1979 Dec;28(6):482-4.
The effect of blood transfusion was analyzed in 194 first cadaver renal transplants and 86 living related renal transplants. The association of blood transfusion with HLA genotyping and poor risk recipients was analyzed. Exclusion of poor risk recipients improved graft survival among the transfused group of patients but not in the small subgroup of nontransfused recipients. No effect of blood transfusion was observed in the living related group. Improved graft survival was observed in both the haplotype-matched and nonhaplotype-matched transfused cadaver recipients. The haplotype-transfused recipients had grafts survival rates of 69 and 66% at 1 and 2 years, respectively. The greatest beneficial effect was seen in the double haplotype-transfused cadaver recipients with graft survival rates of 80 and 71% for the same period. The lack of beneficial effect of transfusion in the living related patients is felt to be a result of the fact that the maximum effect had already been achieved by a far superior donor-recipient histocompatibility than is able to be achieved in a large group of cadaver recipients.
对194例首次尸体肾移植和86例亲属活体肾移植患者的输血效果进行了分析。分析了输血与HLA基因分型及高危受者之间的关联。排除高危受者可提高输血组患者的移植物存活率，但对未输血受者的小亚组无效。在亲属活体肾移植组中未观察到输血的效果。在单倍型匹配和非单倍型匹配的输血尸体肾移植受者中均观察到移植物存活率提高。单倍型输血受者在1年和2年时的移植物存活率分别为69%和66%。在同期双倍型输血尸体肾移植受者中观察到最大的有益效果，移植物存活率分别为80%和71%。亲属活体肾移植患者输血缺乏有益效果被认为是由于供受者组织相容性远优于大多数尸体肾移植受者，已经达到了最大效果。
