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热带地区的甲状腺疾病

Thyroid Disorders in the Tropics

作者信息

Nagendra Lakshmi, Mondal Sunetra, Bhattacharya Saptarshi

机构信息

Department of Endocrinology, JSS Medical College, JSS Academy of Higher Education and Research, Mysore-570004, India

Department of Endocrinology, NRS Medical College, 138 AJC Bose Road, Kolkata-700014, India

PMID:39078930
Abstract

Thyroid disorders are a major cause of non-communicable diseases in developing nations, with the tropical regions presenting unique challenges due to diverse environmental, socio-economic, and cultural factors. Iodine deficiency remains a significant public health concern, leading to conditions such as endemic goiter and cretinism. The prevalence of iodine deficiency disorders has declined due to salt iodization programs, but inconsistent implementation continues to affect many tropical areas. Autoimmune thyroid diseases, including Hashimoto's thyroiditis and Graves' disease are influenced by genetic and environmental factors in the tropics with a minor increase in prevalence following iodization. Thyroiditis, often associated with infections and inflammatory conditions prevalent in tropical regions, add to the complexity. Congenital hypothyroidism, the leading cause of preventable intellectual disability, is challenging to address due to limited newborn screening programs. A multifaceted approach is needed to address these concerns, including improving healthcare infrastructure, increasing public awareness, ensuring consistent iodine supplementation, and enhancing training for healthcare providers. These measures can significantly improve thyroid disorder-related outcomes in tropical nations. For complete coverage of all related areas of Endocrinology, please visit our on-line FREE web-text, WWW.ENDOTEXT.ORG.

摘要

甲状腺疾病是发展中国家非传染性疾病的主要病因,由于环境、社会经济和文化因素多样,热带地区面临着独特的挑战。碘缺乏仍然是一个重大的公共卫生问题,会导致地方性甲状腺肿和克汀病等病症。由于食盐加碘项目,碘缺乏病的患病率有所下降,但实施不一致的情况仍在影响许多热带地区。自身免疫性甲状腺疾病,包括桥本甲状腺炎和格雷夫斯病,在热带地区受遗传和环境因素影响,加碘后患病率略有上升。甲状腺炎通常与热带地区普遍存在的感染和炎症性疾病有关,这增加了复杂性。先天性甲状腺功能减退症是可预防的智力残疾的主要原因,由于新生儿筛查项目有限,解决起来具有挑战性。需要采取多方面的方法来解决这些问题,包括改善医疗基础设施、提高公众意识、确保碘补充的一致性以及加强对医疗服务提供者的培训。这些措施可以显著改善热带国家与甲状腺疾病相关的结果。欲全面涵盖内分泌学的所有相关领域,请访问我们的在线免费网络文本,网址为WWW.ENDOTEXT.ORG。

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