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肥胖患者静脉血栓栓塞病史和同时抗凝治疗的减重和普通外科手术。

Bariatric and general surgical procedures in obese patients with a history of venous thromboembolism and concurrent anticoagulation therapy.

机构信息

Department of Surgery, NYU Langone Hospital-Long Island.

Department of Surgery, NYU-Long Island School of Medicine, Mineola.

出版信息

Cir Cir. 2024;92(4):475-480. doi: 10.24875/CIRU.23000190.

DOI:10.24875/CIRU.23000190
PMID:39079249
Abstract

OBJECTIVE

The objective of this study was to examine the use and outcomes of perioperative anticoagulation (AC) in obese patients with a known history of venous thromboembolism event (VTE).

METHOD

A retrospective review of a prospective database for patients with a VTE history undergoing bariatric and general surgery at a single center (1/2008-12/2017) was performed. Factors assessed included demographics, surgical details, and outcomes.

RESULTS

Sixty-five patients underwent 76 procedures: 46 females (71%); mean age 51 years (range 26-73), mean weight 284 pounds (range 110-558), mean body mass index 45 (range 19-87). Comorbidities include hypertension (60%), gastroesophageal reflux disease (54%), osteoarthritis (49%), obstructive sleep apnea (45%), and diabetes (37%). Operations: 22 general surgeries (29%), 20 sleeve gastrectomies (26%), 12 revisions/conversions (16%), 12 Roux-en-Y gastric bypasses (16%), and 10 gastric bands (13%). Modalities: 67% laparoscopic, 28% robotic, and 5% open. Twenty-two patients (34%) had a pre-operative inferior vena cava filter placed with no complications. The mean length of stay was 4.4 days (range 1-31). Complications: seven 30-day readmissions (9%), one 30-day reoperation (1%), and two 90-day VTEs (3%). Thirty-day readmissions: four for inability to tolerate PO, two for small bowel obstruction, and one for symptomatic anastomotic ulcer.

CONCLUSIONS

In our patients, post-operative AC could be started without an increased risk of bleeding in patients with a history of VTE undergoing bariatric surgery.

摘要

目的

本研究旨在探讨肥胖并伴有静脉血栓栓塞事件(VTE)病史的患者围手术期抗凝(AC)的使用情况及其结局。

方法

对一家单中心(2008 年 1 月至 2017 年 12 月)的 VTE 病史患者接受减重和普外科手术的前瞻性数据库进行回顾性分析。评估的因素包括人口统计学、手术细节和结局。

结果

65 例患者共行 76 例手术:女性 46 例(71%);平均年龄 51 岁(范围 26-73 岁),平均体重 284 磅(范围 110-558 磅),平均体重指数 45(范围 19-87)。合并症包括高血压(60%)、胃食管反流病(54%)、骨关节炎(49%)、阻塞性睡眠呼吸暂停(45%)和糖尿病(37%)。手术类型:普外科手术 22 例(29%)、袖状胃切除术 20 例(26%)、修正术/转化术 12 例(16%)、Roux-en-Y 胃旁路术 12 例(16%)、胃束带术 10 例(13%)。手术方式:腹腔镜 67%、机器人 28%、开放 5%。22 例患者(34%)术前放置了下腔静脉滤器,无并发症发生。平均住院时间为 4.4 天(范围 1-31 天)。并发症:30 天内再入院 7 例(9%)、30 天内再手术 1 例(1%)、90 天内静脉血栓栓塞症 2 例(3%)。30 天内再入院:4 例因无法耐受口服药物、2 例因小肠梗阻、1 例因吻合口溃疡症状性出血。

结论

在我们的患者中,VTE 病史患者在接受减重手术后可以开始使用 AC,而不会增加出血风险。

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