Centre for Diabetes, Endocrinology and Metabolism, University College of Medical Sciences, GTB Hospital, New Delhi, Delhi, 110095, India.
Diabetes Research Society, Hyderabad, Telangana, India.
Diabetes Metab Syndr. 2024 Jul;18(7):103088. doi: 10.1016/j.dsx.2024.103088. Epub 2024 Jul 27.
Short term studies have reported that yoga could be beneficial in preventing diabetes. We evaluated long term effectiveness of yoga in reducing the risk of type 2 diabetes.
This open labelled randomized controlled trial was conducted across five medical centers. Adults diagnosed with prediabetes following an oral glucose tolerance test were randomly assigned to receive a structured yoga intervention consisting of 40 minutes of specific yoga asanas pranayama in addition to standard lifestyle measures or standard lifestyle measures alone. The primary outcome of incident diabetes was compared in both groups at the end of the 3-year intervention period using intention-to-treat analysis.
A total of 974 individuals were randomized (488 to the yoga + lifestyle group-group1 and 486 to the Lifestyle alone group-group2). After 3 years of follow-up, there was a 39.2 % reduction of the relative risk of diabetes with yoga (11.5 % in group1 vs 18.9 % in group 2). Cox proportional hazard model analysis revealed a significantly higher odds ratio of 1.74 (95 % CI 1.25-2.43) of developing diabetes in the lifestyle alone group compared to those who also performed yoga. Adherence to yoga was good with 77 % of individuals performing yoga for more than 75 % of the time.
Structured yoga intervention along with standard lifestyle measures significantly reduces risk of type 2 diabetes when compared with those given lifestyle measures alone.
短期研究报告称，瑜伽可能有益于预防糖尿病。我们评估了瑜伽在降低 2 型糖尿病风险方面的长期效果。
这项开放标签随机对照试验在五个医疗中心进行。在口服葡萄糖耐量试验后被诊断为糖尿病前期的成年人被随机分配接受结构瑜伽干预，包括 40 分钟的特定瑜伽体式和呼吸法，外加标准生活方式措施，或仅接受标准生活方式措施。主要结局是在 3 年干预期结束时，采用意向治疗分析比较两组的新发糖尿病情况。
共有 974 人被随机分组（瑜伽+生活方式组 488 人，组 1；单独生活方式组 486 人，组 2）。随访 3 年后，瑜伽组糖尿病相对风险降低了 39.2%（组 1 为 11.5%，组 2 为 18.9%）。Cox 比例风险模型分析显示，与进行瑜伽的人相比，单独进行生活方式组发生糖尿病的几率明显更高，优势比为 1.74（95%CI 1.25-2.43）。瑜伽的依从性良好，77%的个体进行瑜伽的时间超过 75%。
与单独给予生活方式措施相比，结构化瑜伽干预联合标准生活方式措施可显著降低 2 型糖尿病的风险。
