Samples J R, Baumgartner S D, Binder P S
Cornea. 1985;4(2):118-26.
A 73-year-old man developed a crystalline stromal keratopathy in one eye following his second corneal transplant. Despite aggressive treatment with antibiotics and antifungal agents, the lesion increased in size. A corneal transplant was performed and histopathologic studies were performed using both light and transmission electron microscopy. The characteristic trilamellar structure of a bacterial cell wall was found. The organisms were present only anteriorly. Small electron-dense bodies with needle-like projections were found. These bodies may be responsible for the crystalline appearance of this keratopathy. The appearance of a crystalline keratopathy should alert clinicians to the possibility of a low-grade bacterial infection. After appropriate cultures, we advise early and aggressive therapy with appropriate antibiotics.
一名73岁男性在第二次角膜移植后一只眼睛发生了结晶性基质角膜病变。尽管使用抗生素和抗真菌药物进行了积极治疗，但病变仍增大。进行了角膜移植，并使用光学显微镜和透射电子显微镜进行了组织病理学研究。发现了细菌细胞壁的特征性三层结构。这些微生物仅存在于前部。发现了带有针状突起的小电子致密体。这些小体可能是这种角膜病变结晶外观的原因。结晶性角膜病变的出现应提醒临床医生注意低度细菌感染的可能性。在进行适当培养后，我们建议早期使用适当的抗生素进行积极治疗。
