Department of Pathology, Tribhuvan University Teaching Hospital, Maharajgunj, Kathmandu, Nepal.
DI Skin Hospital and Referral Centre Private Ltd, Bansbari, Budanilkantha, Kathmandu, Nepal.
J Nepal Health Res Counc. 2024 Jun 22;22(1):123-129. doi: 10.33314/jnhrc.v22i01.4879.
Primary cutaneous lymphomas are a distinct group of rare lymphoid neoplasms with absence of extracutaneous lymphomas at the time of presentation. They are rare in Nepal and no data on cutaneous lymphoma have been published from this country till date.
This retrospective study included 15 cases of cutaneous lymphomas retrieved from the records of department of Dermatopathology, DI Skin Hospital and Referral Centre, Bansbari, Kathmandu, Nepal. Patients were diagnosed according to the current WHO classification for cutaneous lymphoma.
A total of 15 cases were studied with median age of 45 years (range: 22 to 81 years) and male to female ratio of 1.5:1. Primary cutaneous lymphomas constituted 13 cases out of 15 and the most common type of cutaneous lymphoma was mycosis fungoides and variants 5 (33%), followed by CD30 positive primary cutaneous anaplastic large cell lymphoma constituting 2 (13%). T-cell cutaneous lymphoma constituted 13 (87%) and B-cell cutaneous lymphoma 2 (13%).
Cutaneous T-cell lymphomas were more frequent than cutaneous B-cell lymphomas in Nepalese patients. Mycosis fungoides and variants are commonest type of primary cutaneous lymphomas.
原发性皮肤淋巴瘤是一组罕见的淋巴肿瘤，在发病时不存在皮肤外淋巴瘤。在尼泊尔，原发性皮肤淋巴瘤较为罕见，迄今为止，尚无来自该国的皮肤淋巴瘤数据。
本回顾性研究纳入了来自尼泊尔加德满都班萨里 DI 皮肤医院和转诊中心皮肤科病理科记录的 15 例皮肤淋巴瘤病例。根据目前的世界卫生组织（WHO）皮肤淋巴瘤分类对患者进行诊断。
共研究了 15 例患者，中位年龄为 45 岁（范围：22 岁至 81 岁），男女比例为 1.5:1。原发性皮肤淋巴瘤占 15 例中的 13 例，最常见的皮肤淋巴瘤类型是蕈样真菌病和变异型 5（33%），其次是 CD30 阳性原发性皮肤间变性大细胞淋巴瘤，占 2 例（13%）。T 细胞皮肤淋巴瘤占 13 例（87%），B 细胞皮肤淋巴瘤占 2 例（13%）。
在尼泊尔患者中，T 细胞皮肤淋巴瘤比 B 细胞皮肤淋巴瘤更为常见。蕈样真菌病和变异型是最常见的原发性皮肤淋巴瘤类型。
