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新生儿破伤风病例系列:埃塞俄比亚亚的斯亚贝巴圣保罗医院千禧医学院的生存与悲剧故事

Neonatal Tetanus Case Series: A Tale of Survival and Tragedy at St Paul Hospital Millennium Medical College, Addis Ababa, Ethiopia.

作者信息

Bacha Tigist, Abayneh Mahlet, Tefera Dawit Bekele

机构信息

Division of Pediatric Emergency and Critical Care, Department of Pediatrics and Child Health St Paul Hospital Millennium Medical College, Addis Ababa, Ethiopia.

Division of Neonatology Department of Pediatrics and Child Health St Paul Hospital Millennium Medical College, Addis Ababa, Ethiopia.

出版信息

Pediatric Health Med Ther. 2024 Jul 26;15:257-264. doi: 10.2147/PHMT.S456550. eCollection 2024.

Abstract

BACKGROUND

Neonatal tetanus remains a significant threat in regions with limited healthcare access, despite being preventable through vaccination. The case-fatality rate of untreated neonatal tetanus is close to 100%. Even one case of neonatal tetanus regarded as a failure of the healthcare system, making it essential to remain mindful of this disease's relevance to public health. Two cases of neonatal tetanus are presented, highlighting the severe consequences of the disease. One infant survived after ICU treatment, while the other succumbed despite medical intervention.

CONCLUSION

These cases underscore the critical need for clean delivery practices and Tetanus anti-toxoid vaccination for women of reproductive age. Improving access to quality antenatal healthcare and promoting clean birth practices are essential in reducing the incidence of neonatal tetanus and preventing unnecessary deaths.

摘要

背景

尽管可通过接种疫苗预防,但在医疗保健服务有限的地区,新生儿破伤风仍然是一个重大威胁。未经治疗的新生儿破伤风病死率接近100%。即使出现一例新生儿破伤风病例也被视为医疗系统的失败,因此必须始终牢记这种疾病对公共卫生的影响。本文介绍了两例新生儿破伤风病例,突出了该疾病的严重后果。一名婴儿在重症监护病房治疗后存活,而另一名婴儿尽管接受了医疗干预仍不幸死亡。

结论

这些病例强调了对育龄妇女进行清洁接生做法和破伤风抗毒素疫苗接种的迫切需求。改善获得优质产前保健的机会并推广清洁分娩做法对于降低新生儿破伤风发病率和预防不必要的死亡至关重要。

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本文引用的文献

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Maternal and neonatal tetanus.孕产妇和新生儿破伤风
Lancet. 2015 Jan 24;385(9965):362-70. doi: 10.1016/S0140-6736(14)60236-1. Epub 2014 Aug 19.
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Diazepam for treating tetanus.地西泮用于治疗破伤风。
Cochrane Database Syst Rev. 2004;2004(1):CD003954. doi: 10.1002/14651858.CD003954.pub2.

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